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首页> 外文期刊>Journal of Autism and Developmental Disorders >Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder
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Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder

机译：与注意缺陷/多动症相比，自闭症谱系障碍成年人的反应抑制

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摘要

Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are hypothesised to involve core deficits in executive function. Previous studies have found evidence of a double dissociation between the disorders on specific executive functions (planning and response inhibition). To date most research has been conducted with children. No studies have directly compared the stable cognitive profile of adults. It was hypothesised that adults with ASD would show generally intact response inhibition whereas those with ADHD would show more global impairment. Participants were 24 adults aged 18–55 with high functioning ASD, 24 with ADHD, and 14 age and IQ matched controls. Participants completed three standardised measures of response inhibition. Participants with ASD had generally intact response inhibition but slow response latencies, possibly due to deficits in response initiation. Adults with ADHD did not show the more global impairments hypothesised. There were some significant differences between the clinical groups across measures of inhibition. In terms of performance style, adults with ASD were slow and accurate whilst those with ADHD showed an impulsive style.
机译：据认为自闭症谱系障碍（ASD）和注意力缺陷/多动障碍（ADHD）涉及执行功能的核心缺陷。先前的研究发现，在特定执行功能（计划和反应抑制）方面，疾病之间存在双重解离的证据。迄今为止，大多数研究都是针对儿童进行的。没有研究直接比较成年人的稳定认知状况。据假设，患有ASD的成年人通常会表现出完整的反应抑制，而患有ADHD的成年人会表现出更多的整体损伤。参加者为24位18-55岁的成人，具有较高的ASD功能，其中24位患有ADHD，以及14位年龄和智商匹配的对照组。参与者完成了三种抑制反应的标准化措施。患有ASD的参与者通常具有完整的反应抑制能力，但反应潜伏期较慢，这可能是由于反应启动不足所致。患有多动症的成年人并未显示出更多的假设性总体损害。在抑制措施方面，临床组之间存在一些显着差异。就表演风格而言，患有ASD的成年人缓慢而准确，而患有ADHD的成年人表现出冲动的风格。

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