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MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan

机译：MMR疫苗和自闭症谱系回归：来自日本的负面结果

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摘要

It has been suggested that the measles, mumps, and rubella vaccine (MMR) is a cause of regressive autism. As MMR was used in Japan only between 1989 and 1993, this time period affords a natural experiment to examine this hypothesis. Data on 904 patients with autism spectrum disorders (ASD) were analyzed. During the period of MMR usage no significant difference was found in the incidence of regression between MMR-vaccinated children and non-vaccinated children. Among the proportion and incidence of regression across the three MMR-program-related periods (before, during and after MMR usage), no significant difference was found between those who had received MMR and those who had not. Moreover, the incidence of regression did not change significantly across the three periods.
机译：有人提出麻疹，腮腺炎和风疹疫苗（MMR）是自闭症退步的原因。由于MMR仅在1989年至1993年间在日本使用，因此这段时间为检验这一假设提供了自然的实验。分析了904例自闭症谱系障碍（ASD）患者的数据。在使用MMR期间，接种MMR的儿童和未接种MMR的儿童之间的回归发生率没有显着差异。在三个与MMR计划相关的时期（使用MMR之前，期间和之后）的回归比例和发生率之间，未接受MMR的人与未接受MMR的人之间没有发现显着差异。此外，在这三个时期中回归的发生率没有显着变化。

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  • 来源
    《Journal of Autism and Developmental Disorders》 |2007年第2期|210-217|共8页
  • 作者

    Tokio Uchiyama; Michiko Kurosawa; Yutaka Inaba;

  • 作者单位

    Department of Human Welfare Otsuma Women’s University 2-7-1 Karakida Tama-city Tokyo 206-8540 Japan;

    Department of Epidemiology and Environmental Health Juntendo University School of Medicine Tokyo Japan;

    Department of Epidemiology and Environmental Health Juntendo University School of Medicine Tokyo Japan;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    MMR; Autism; ASD; Regression;

    机译：MMR;自闭症;ASD;回归;

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