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Video Analysis of Sensory-Motor Features in Infants with Fragile X Syndrome at 9–12 Months of Age

机译:9-12月龄脆性X综合征婴儿的感觉运动特征的视频分析

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摘要

This study utilized retrospective video analysis to distinguish sensory-motor patterns in infants with fragile X syndrome (FXS) (n=11) from other infants [i.e., autism (n=11), other developmental delay (n=10), typical (n=11)] at 9–12 months of age. Measures of development, autistic features, and FMRP were assessed at the time of entry into the study. Home videos collected from families were edited and coded with previously validated procedures. Findings revealed a pattern of sensory-motor features (e.g., repetitive leg movements, posturing, less sophistication/repetitive use of objects) associated with FXS, and suggest these infants were most similar to the group of infants with other developmental delays, irrespective of co-existing autistic symptoms later in life. Infant sensory-motor features in the FXS group were more predictive of an early developmental milestone (i.e., age walking) than later, more broad, developmental outcomes, or FMRP. Implications for early identification and differential diagnosis are discussed.
机译:这项研究利用回顾性视频分析来区分脆性X综合征(FXS)(n = 11)婴儿与其他婴儿[即自闭症(n = 11),其他发育迟缓(n = 10),典型( n = 11)]在9-12个月大时。进入研究时评估了发育,自闭症特征和FMRP的量度。从家庭收集的家庭视频经过编辑和编码,并经过了事先验证的程序。研究发现揭示了与FXS相关的感觉运动特征(例如,重复性的腿部运动,姿势,较少的复杂性/重复使用物体)的模式,并且表明这些婴儿与其他发育迟缓的婴儿组最为相似,无论在以后的生活中存在自闭症症状。 FXS组的婴儿感觉运动功能比早期,更广泛的发育结果或FMRP更能预示早期的发展里程碑(即年龄增长)。讨论了对早期识别和鉴别诊断的意义。

著录项

  • 来源
    《Journal of Autism and Developmental Disorders》 |2005年第5期|645-656|共12页
  • 作者单位

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel HillDivision of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

    Division of Occupational Science Department of Allied Health Sciences University of North Carolina at Chapel Hill;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Home movies; mental retardation; fragile X syndrome (FXS); autism; sensorimotor development; infancy;

    机译:家庭电影;智力低下;易碎X综合征(FXS);自闭症;感觉运动发育;婴儿期;

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