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首页> 外文期刊>Journal of Autism and Developmental Disorders >Plasma Amino Acid Levels in Children with Autism and Their Families
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Plasma Amino Acid Levels in Children with Autism and Their Families

机译：自闭症儿童及其家庭的血浆氨基酸水平

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摘要

Plasma amino acid levels were measured in autistic and Asperger syndrome patients, their siblings, and parents. The results were compared with values from age-matched controls. Patients with autism or Asperger syndrome and their siblings and parents all had raised glutamic acid, phenylalanine, asparagine, tyrosine, alanine, and lysine (p < .05) than controls, with reduced plasma glutamine. Other amino acids were at normal levels. These results show that children with autistic spectrum disorders come from a family background of dysregulated amino acid metabolism and provide further evidence for an underlying biochemical basis for the condition.
机译：在自闭症和阿斯伯格综合症患者，其兄弟姐妹和父母中测量血浆氨基酸水平。将结果与年龄匹配的对照组的值进行比较。自闭症或阿斯伯格综合症患者及其兄弟姐妹和父母的父母都比对照组的谷氨酸，苯丙氨酸，天冬酰胺，酪氨酸，丙氨酸和赖氨酸升高（p <.05），血浆谷氨酰胺降低。其他氨基酸处于正常水平。这些结果表明，患有自闭症谱系障碍的儿童来自氨基酸代谢失调的家庭背景，并为该病的潜在生化基础提供了进一步的证据。

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