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Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry

机译:缺乏乳制品行业中与乳酸菌协同作用引起的IgE过敏致敏的证据

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摘要

This research communication aimed to evaluate the level of immunoglobulin E from lactic acid bacteria (LAB) that are used in dairy industries. Previous studies have demonstrated that workers report symptoms of irritation and are frequently IgG-sensitised to LAB. Workers (n = 44) from a pro-biotic production unity and the control lab were seen by a medical practitioner and responded to an occupational questionnaire. Specific IgE by the DELFIA® technique against 6 strains of LAB were measured on 44 exposed workers and 31 controls sera. Levels of specific IgE were low and no difference was observed between the two groups. This lack of IgE response could be explained by a healthy worker effect, an efficient implementation of personal protective equipment or by an absence of allergic mechanisms to account for the self-reported irritative symptoms. Despite the high concentrations of LAB, preventive measures are effective enough to guarantee no allergic effect and to prevent other adverse health effects. The implementation of preventive measures to avoid or reduce exposure to dust of LAB, and more generally to milk powder, is recommended in all dairy industry.
机译:该研究通讯旨在评估乳制品行业中使用的乳酸菌(LAB)产生的免疫球蛋白E的水平。先前的研究表明,工人报告有刺激症状,并经常对LAB进行IgG致敏。来自益生菌生产单位和控制实验室的工人(n = 44)被医生发现并回答了职业问卷。通过DELFIA®技术,对44名裸露工人和31名对照血清测量了针对6株LAB的特异性IgE。特异性IgE水平较低,两组之间没有观察到差异。缺乏IgE反应的原因可以归结为工人健康的健康,有效实施个人防护设备或缺乏过敏机制来解释自我报告的刺激性症状。尽管LAB的浓度很高,但预防措施仍然足够有效,以确保没有过敏作用并防止其他不良健康影响。在所有乳制品行业中,建议采取预防措施以避免或减少LAB灰尘的暴露,更普遍地避免暴露于奶粉的灰尘。

著录项

  • 来源
    《Journal of dairy research》 |2018年第3期|355-357|共3页
  • 作者单位

    UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Pare, 25030 Besançon, France,Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France;

    UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Pare, 25030 Besançon, France,Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France;

    UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Pare, 25030 Besançon, France,Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France;

    UMR/CNRS 6249 Chrono-Environnement, University of Bourgogne Franche-Comté, UFR Sciences médicales et pharmaceutiques, 19 rue Ambroise Pare, 25030 Besançon, France,Department of Parasitology-Mycology, University Hospital, 2Bd Fleming, 25030 Besançon, France;

    Institute of Work and Health, University of Lausanne, route de la Comiche 2, 1066 Epalinges-Lausanne, Switzerland;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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