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The use of bacteriophages of the family Cystoviridae as surrogates for H5N1 highly pathogenic avian influenza viruses in persistence and inactivation studies

机译:在持续性和灭活研究中,将cystoviridae家族的噬菌体用作H5N1高致病性禽流感病毒的替代物

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摘要

Two bacteriophages, φ6 and φ8, were investigated as potential surrogates for H5N1 highly pathogenic avian influenza virus in persistence and chlorine inactivation studies in water. In the persistence studies, φ6 and φ8 remained infectious at least as long as the H5N1 viruses at both 17 and 28℃ in fresh water, but results varied in salinated water. The bacteriophage φ6 also exhibited a slightly higher chlorine resistance than that of the H5N1 viruses. Based upon these findings, the bacteriophages may have potential for use as surrogates in persistence and inactivation studies in fresh water.
机译:在水中的持续性和氯灭活研究中,研究了两种噬菌体φ6和φ8作为H5N1高致病性禽流感病毒的潜在替代物。在持久性研究中,只要在17和28℃的淡水中,φ6和φ8仍具有传染性,至少与H5N1病毒一样长,但盐化水中的结果却有所不同。噬菌体φ6还显示出比H5N1病毒略高的耐氯性。基于这些发现,噬菌体可能有潜力在淡水的持久性和灭活研究中用作替代物。

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