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首页> 外文期刊>Journal of Food Science >A Cherry Seed-Derived Spice, Mahleb, is Recognized by Anti-Almond Antibodies Including Almond-Allergic Patient IgE
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A Cherry Seed-Derived Spice, Mahleb, is Recognized by Anti-Almond Antibodies Including Almond-Allergic Patient IgE

机译：樱桃种子衍生的香料Mahleb被包括杏仁过敏患者IgE在内的抗杏仁抗体所认可

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摘要

There are a number of examples of immunologic cross-reactivity elicited by pollens, fruits, seeds, and nuts of closely related plant species. Such cross-reactivity is of particular concern for patients with food allergies. In this report, we investigated a spice (mahleb) that is prepared from the kernel of the St. Lucie cherry, Prunus mahaleb, for cross-reactivity with almond (Prunus dulcis), using enzyme-linked immunosorbent assay (ELISA) and Western blot. Almond and mahleb are members of the same genus. Cross-reactivity between the mahleb and almond was demonstrated by reaction of cherry and almond kernel protein extracts with antibodies raised against almond proteins. Almond-specific murine monoclonal IgG, rabbit polyclonal IgG, and almond-allergic serum IgE each exhibited cross-reactivity with cherry kernel protein. Because of the demonstrated cross-reactivity between almond and mahleb, these findings should be of special concern to almond-allergic patients and attending medical personnel.
机译：由密切相关的植物物种的花粉，果实，种子和坚果引起的免疫交叉反应的例子有很多。对于食物过敏的患者，这种交叉反应特别令人关注。在本报告中，我们使用酶联免疫吸附测定（ELISA）和Western印迹法研究了一种由圣露西樱桃仁（Prunus mahaleb）的核仁制备的香料（mahleb）与杏仁（Prunus dulcis）的交叉反应性。 。杏仁和马勒布属于同一属。通过樱桃和杏仁仁蛋白提取物与针对杏仁蛋白的抗体的反应，证明了锦缎与杏仁之间的交叉反应性。杏仁特异性鼠类单克隆IgG，兔多克隆IgG和杏仁过敏性血清IgE均表现出与樱桃仁蛋白的交叉反应性。由于杏仁和马勒布之间表现出交叉反应性，因此这些发现应引起杏仁过敏患者和医疗人员的特别关注。

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  • 来源
    《Journal of Food Science》 |2017年第9期|1786-1791|共6页
  • 作者

    Kyle A. Noble; Changqi Liu; Shridhar K. Sathe; Kenneth H. Roux;

  • 作者单位

    Dept. of Biological Science, 319 Stadium Dr., Florida State Univ., Tallahassee, FL 32306-4370, U.S.A.;

    Dept. Nutrition, Food (it Exercise Sciences, 120 Convocation Way, Florida State University, Tallahassee, FL 32306-1493, U.S.A.;

    Dept. Nutrition, Food (it Exercise Sciences, 120 Convocation Way, Florida State University, Tallahassee, FL 32306-1493, U.S.A.;

    Dept. of Biological Science, 319 Stadium Dr., Florida State Univ., Tallahassee, FL 32306-4370, U.S.A.;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    almond; cherry seed; cross-reactivity; food allergy; mahleb;

    机译：杏仁;樱桃种子交叉反应食物过敏;马勒布;

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