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首页> 外文期刊>Journal of Materials Research >Synthesis and blood compatibilities of novel segmented polyurethanes containing phosphatidylcholine analogous moieties in the main chains and long-chain alkyl groups in the side chains
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Synthesis and blood compatibilities of novel segmented polyurethanes containing phosphatidylcholine analogous moieties in the main chains and long-chain alkyl groups in the side chains

机译：主链上含有磷脂酰胆碱类似部分且侧链上具有长链烷基的新型分段聚氨酯的合成和血液相容性

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摘要

New segmented polyurethanes containing phospholipid moieties in the main chains and long-chain alkyl groups in the side chains were synthesized. The soft segments used in this study were poly(butadiene), poly(isoprene), hydrogenated poly(isoprene), and poly(1,6-hexyl- l,2-ethylcarbonate) diol. The hard segments of these polyurethanes were 4,4l-methylenediphenyl dilsocyanate, bis[2-(2-hydroxyethyldhethylamin l,3-propanediphosphate, and l,4-butanediol. The blood compatibilities of the new polymers were evaluated by platelet-rich plasma contact studies and viewed by scanning electron microscopy using medical grade Biospan and nonphospholipid polyurethane as references. These new materials have good surfaces in terms of platelet adhesion, and the morphology of adhered platelets undergoes a relatively low degree of variation.
机译：合成了在主链中包含磷脂部分和在侧链中包含长链烷基的新型链段聚氨酯。在本研究中使用的软链段是聚（丁二烯），聚（异戊二烯），氢化聚（异戊二烯）和聚（1,6-己基-1,2-乙基碳酸酯）二醇。这些聚氨酯的硬链段是4,4l-亚甲基二苯基二异氰酸酯，双[2-（2-羟乙基dhethylaminl，3-丙烷二磷酸酯和l，4-丁二醇）。通过富血小板血浆接触评估了新聚合物的血液相容性这些新材料在血小板粘附方面具有良好的表面，并且粘附的血小板的形态变化程度相对较低，这些研究和研究均以医用级Biospan和非磷脂聚氨酯为参考的扫描电子显微镜进行了观察。

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