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A soft-lithographed chaotic electrokinetic micromixer for efficient chemical reactions in lab-on-chips

机译:用于在芯片实验室中进行有效化学反应的软光刻混沌电动微混合器

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摘要

Mixing is one of the basic functions which automated lab-on-chips require for the effective management of liquid samples. In this paper we report on the working principle, design, fabrication and experimental characterization of a soft-lithographed micromixer for microfluidic applications. The device effectively mixes two liquids by means of chaotic advection obtained as an implementation of a Linked Twisted Map (LTM). In this sense it is chaotic. The liquids are electrokinetically displaced by generating rolls through AC electroosmosis on co-planar electrodes. The device performance has been tested on dyed DI-water for several voltages, frequencies and flow-rates, displaying good mixing properties in the range of 10÷100 kHz, at low peak-to-peak voltages (~ 15H÷20 volts). Low voltage supply, small dimensions and possibility of fabrication via standard lithographic techniques make the device highly integrable in lab-on-a-chip platforms.
机译:混合是自动芯片实验室对液体样品进行有效管理所需的基本功能之一。在本文中,我们报告了用于微流体应用的软光刻微混合器的工作原理,设计,制造和实验特性。该设备通过作为链接扭曲图(LTM)的实现而获得的混沌对流有效地混合了两种液体。从这个意义上讲,它是混乱的。通过在共面电极上通过交流电渗透产生辊,从而使液体电动移动。该设备的性能已经在染色的去离子水上测试了多种电压,频率和流速,在低峰峰值电压(约15H÷20伏)下,在10÷100 kHz的范围内显示出良好的混合性能。低压电源,小尺寸以及通过标准光刻技术制造的可能性,使该器件高度集成在片上实验室平台中。

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