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首页> 外文期刊>Journal of Oleo Science >Effect of Combination Therapy of Fatty Acids, Calcium, Vitamin D and Boron with Regular Physical Activity on Cardiovascular Risk Factors in Rat
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Effect of Combination Therapy of Fatty Acids, Calcium, Vitamin D and Boron with Regular Physical Activity on Cardiovascular Risk Factors in Rat

机译：定期体育锻炼的脂肪酸，钙，维生素D和硼联合治疗对大鼠心血管危险因素的影响

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摘要

The effect of consumption of fatty acids and selected nutrients, along with regular physical activity, on cardiovascular risk factors in rats was investigated. Male rats were divided into the seven groups: Group 1: regular food and drinking water, Group 2: same as Group. 1 + physical activity (whole body vibration; WBV), Group 3: same as Group. 2 + calcium, vitamin D, boron, Group 4: same as Group. 3 + canola oil, Group 5: same as Group. 3 + sunflower oil, Group 6: same as Group. 3 + mix of sunflower oil and canola oil, Group 7: same as Group. 3 + coconut oil. Rats were treated for 8 weeks, and analysis of the frozen plasmas was performed. A- Analysis between the treatment groups and control revealed that vibration training in Group 2 increased body weight (P = 0.04), plasma creatin kinase (CK), (P = 0.02), and estradiol (E2), (P = 0.03). Rats in Group 5 consumed less food and plasma levels of cholesterol and LDL-cholesterol (LDL-C) increased significantly (P = 0.02) in Group 6 and in Group 7 (p<0.05). B- Analysis of data among Group 4-7 (the oil consuming groups) and Group 3 revealed significant differences in cholesterol (Choi), LDL-C, HDL-cholesterol (HDL-C), triglycerides (TG), C- reactive protein (hs-CRP), estradiol (E2), atherogenic index (AI), and risk factor (RF), (p<0.05). In addition, plasma levels of testosterone (T) and free testosterone (FT) in Group 7 had a remarkable but nonsignificant increase. As a result of vibration training, a similar trend was observed for vitamin D in Group 2-7. The findings show that WBV is effective in improving health status by influencing cardiovascular disease (CVD) risk factors. Moreover, canola oil and sunflower oil, separately, showed beneficial impacts on CVD risk factors; whereas their combination had negative impacts on lipid profile. Coconut oil revealed to be efficient to provide health benefits in terms of CVD treatments.
机译：研究了食用脂肪酸和选定营养素以及定期进行体育锻炼对大鼠心血管危险因素的影响。将雄性大鼠分为七个组：第一组：常规食物和饮用水，第二组：与第二组相同。 1 +身体活动（全身振动； WBV），组3：与组相同。 2 +钙，维生素D，硼4组：与组相同。 3 +菜籽油，第5组：与第3组相同。 3 +葵花籽油，第6组：与第组相同。 3 +葵花籽油和低芥酸菜子油的混合物，第7组：与第组相同。 3 +椰子油。将大鼠治疗8周，并对冷冻血浆进行分析。 A-治疗组和对照组之间的分析表明，第2组的振动训练增加了体重（P = 0.04），血浆肌酐激酶（CK）（P = 0.02）和雌二醇（E2）（P = 0.03）。第5组的大鼠食用较少的食物，并且第6组和第7组的胆固醇和LDL-胆固醇（LDL-C）血浆水平显着增加（P = 0.02）（p <0.05）。 B-第4-7组（耗油组）与第3组之间的数据分析表明，胆固醇（Choi），LDL-C，HDL-胆固醇（HDL-C），甘油三酸酯（TG）和C-反应蛋白存在显着差异（hs-CRP），雌二醇（E2），动脉粥样硬化指数（AI）和危险因素（RF），（p <0.05）。此外，第7组的血浆睾丸激素（T）和游离睾丸激素（FT）含量有显着但无显着增加。振动训练的结果是，在第2-7组中观察到了维生素D的类似趋势。研究结果表明，WBV可通过影响心血管疾病（CVD）危险因素有效改善健康状况。此外，菜籽油和葵花籽油分别对CVD危险因素显示出有益的影响。而它们的组合对血脂水平有负面影响。椰子油在CVD治疗方面可有效提供健康益处。

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  • 来源
    《Journal of Oleo Science》 |2012年第2期|p.103-111|共9页
  • 作者

    M. R. Naghii; P. Darvishi; Y. Ebrahimpour; G. Ghanizadeh; M. Mofid; M. Hedayati; A. R. Asgari;

  • 作者单位

    Sport Physiology Research Center, and Health School, Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Health School , Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Health School , Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Health School , Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Department of Anatomy, Faculty of Medicine, Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

    Sport Physiology Research Center, and Health School, Baqiyatallah (a.s.) University of Medical Sciences, Tehran, ISLAMIC REPUBLIC OF IRAN;

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  • 正文语种 eng
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  • 关键词

    cardiovascular disease; fatty acids; calcium; boron; vitamin D; vibration;

    机译：心血管疾病;脂肪酸;钙;硼;维生素D;振动;

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