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The impact of early-life economic conditions on cause-specific mortality during adulthood

机译:早期经济状况对成年期间特定原因死亡率的影响

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The aim of this study is to assess the effects of economic conditions in early life on cause-specific mortality during adulthood. The analyses are performed on a unique historical sample of 14,520 Dutch individuals born in 1880-1918, who are followed throughout life. The economic conditions in early life are characterized using cyclical variations in annual real per capital gross domestic product during pregnancy and the first year of life. Exposure to recessions in early life appears to significantly increase cancer mortality risks of older males and females. It also significantly increases other mortality risks especially for older females. The residual life expectancies are up to about 8 and 6 % lower for male and female cancer mortality, respectively, and up to about 5 % lower for female cardiovascular mortality. Our analyses show that cardiovascular and cancer mortality risks are related and that not taking this association into account leads to biased inference.
机译:这项研究的目的是评估成年期间经济状况对特定原因死亡率的影响。分析是对14520名出生于1880-1918年的荷兰人的独特历史样本进行的,这些人终生受到关注。孕早期和生命的第一年中,早期生活中的经济状况的特征在于其年实际人均国内生产总值的周期性变化。早期生活中的衰退似乎显着增加了老年男性和女性的癌症死亡风险。它还显着增加了其他死亡风险,特别是对于老年女性。男性和女性癌症死亡率的预期剩余寿命分别降低约8%和6%,女性心血管疾病死亡率的预期剩余寿命降低约5%。我们的分析表明,心血管疾病和癌症的死亡风险是相关的,并且不考虑这种关联会导致偏差推断。

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