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首页> 外文期刊>The Journal of the Textile Institute >Effect of solvent on the physicochemical properties of electrospun nanocomposite with gamat oil and cerium oxide for potential medical engineering application
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Effect of solvent on the physicochemical properties of electrospun nanocomposite with gamat oil and cerium oxide for potential medical engineering application

机译：溶剂对电纺纳米复合材料用沙巴玻璃和氧化铈进行医学工程应用的影响

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摘要

Wound healing is a complex and intricate process that has affected millions of people due to improper management. Scaffolds are capable of exhibiting an environment that is optimum for the regeneration of damaged tissues and hence, enhances the process of wound healing. The current study was done to fabricate nanocomposites composed of polycaprolactone (PCL) as well as gamat oil and cerium (Ce) oxide particles of different ratios through electrospinning that can be used in the healing of wounds. The polymeric solutions were dissolved in two different solvent systems to investigate the influence of solvent parameters on the physical properties of nanofibres. Solvent system A was a mixture of chloroform and dimethylformamide (DMF), while solvent system B was a mixture of acetone and DMF. Morphological analysis of fibre diameter indicated a decrease and the reduction of diameter was more pronounced in solvent system B rather than A. Contact angle measurements revealed that the addition of added constituents to pure PCL have increased its' hydrophobicity nature for nanocomposites using both solvent systems. Fourier transform infrared spectroscopy (FTIR) results indicated chemical interactions between PCL, gamat oil and cerium oxide as detected through the shift in absorption bands. Lastly, mechanical testing of the nanocomposites indicated that using both solvent systems, there was an increase in the tensile strengths when gamat oil and Ce oxide were added. The newly fabricated nanocomposites using different solvent systems demonstrated physicochemical properties that are well suited for wound healing applications.
机译：伤口愈合是一种复杂和复杂的过程，由于管理不当而受到数百万人的影响。支架能够表现出对受损组织再生最佳的环境，因此增强了伤口愈合的过程。完成目前的研究以制造由聚己内酯（PCL）组成的纳米复合材料，以及通过可用于伤口愈合的静电纺丝的不同比例的Gamat油和氧化铈（Ce）氧化物颗粒。将聚合物溶液溶解在两种不同的溶剂体系中，以研究溶剂参数对纳米纤溴的物理性质的影响。溶剂系统A是氯仿和二甲基甲酰胺（DMF）的混合物，而溶剂系统B是丙酮和DMF的混合物。纤维直径的形态学分析表明，溶剂系统B中的直径降低更加明显，而不是A.接触角测量表明，使用两种溶剂系统增加加入的添加成分对纯PCL的疏水性。傅里叶变换红外光谱（FTIR）结果表明通过在吸收带中检测到的PCL，Gamat油和氧化铈之间的化学相互作用。最后，纳米复合材料的机械测试表明，使用两个溶剂系统，加入Gamat油和Ce氧化物时抗拉强度的增加。使用不同溶剂系统的新制造的纳米复合材料表明了伤口愈合应用的物理化学性质。

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