• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Materials Research Innovations >Mesoporous bioactive glass: ideal material for higher uptake and well sustained release of ibuprofen
【24h】

Mesoporous bioactive glass: ideal material for higher uptake and well sustained release of ibuprofen

机译：介孔生物活性玻璃：布洛芬具有更高的摄取和良好的持续释放的理想材料

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Mesoporous bioactive glass (MBG) and mesoporous silica (MS) have been synthesised bynevaporation induced self-assembly method. Both samples possess ordered mesoporousnstructure and grainy morphologies. Ibuprofen was used as model drug, and the drug loadingnand release process were studied in detail. The MBG shows a higher drug loading capacity (46%)nthan that of MS (28%) due to its high surface area and pore volume and the stronger interactionnbetween ibuprofen and Ca2z of MBG. The release profile investigation of both samples indicatednthat MBG has a longer and gentle drug release process than that of MS. It can be found that MBGnhas the advantages for controlled release, such as higher drug loading capacity and long releaseneffect, which makes MBG a good candidate for drug carrier.
机译：通过蒸发诱导自组装法合成了介孔生物活性玻璃（MBG）和介孔二氧化硅（MS）。两种样品均具有有序的介孔结构和粒状形态。以布洛芬为模型药物，详细研究了其载药量和释放过程。 MBG具有较高的表面积和孔体积，且布洛芬与MBG的Ca2z之间具有更强的相互作用，因此与MS（28％）相比，具有更高的载药量（46％）n。两种样品的释放曲线研究表明，MBG的释放过程比MS的释放过程更长且更温和。可以发现MBGn具有控释的优点，例如更高的载药量和长效释放，这使得MBGn成为药物载体的良好候选者。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号