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Synthesis and in vitro bioactivity of mesoporous bioactive glass scaffolds

机译:介孔生物活性玻璃支架的合成及体外生物活性

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摘要

The main objective of the present study was to determine the effect of thermal treatment procedures (calcination temperature, heating rate and duration time) on the synthesis of SiO_2-CaO-P_2O_5 mesoporous bioactive glass scaffolds. This is accomplished by thermogravimetric analyses, Fourier transform infrared (FTIR) absorption spectra, X-ray diffraction (XRD) and by analysis of nitrogen adsorption/desorption isotherms. In vitro bioactivity can also be assessed by the cytotoxic effect of the glasses on the N1H-3T3 cell line, and by characterization of MC-3T3-E1 cell attachment.
机译:本研究的主要目的是确定热处理程序(煅烧温度,加热速率和持续时间)对SiO_2-CaO-P_2O_5介孔生物活性玻璃支架合成的影响。这可以通过热重分析,傅立叶变换红外(FTIR)吸收光谱,X射线衍射(XRD)以及氮吸附/解吸等温线的分析来实现。还可以通过眼镜对N1H-3T3细胞系的细胞毒作用,以及通过表征MC-3T3-E1细胞附着来评估体外生物活性。

著录项

  • 来源
    《Materials science & engineering》 |2010年第5期|p.657-663|共7页
  • 作者单位

    Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan;

    Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan;

    School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan;

    Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan;

    Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan;

    Department of Orthopaedic Surgery, Chang-Hua Christian Hospital, Changhua 500, Taiwan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    mesoporous; bioactive glasses; scaffold; NIH-3T3; MC-3T3-E1;

    机译:中孔生物活性玻璃脚手架;NIH-3T3;MC-3T3-E1;

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