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Biosensing application of multiwall boron nitride nanotube-based nanoresonator for detecting various viruses

机译：多壁氮化硼纳米管基纳米共振器在生物检测中的生物传感应用

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This study explores the suitability of biosensors using multi-walled boron nitride nanotubes (MW-BNNTs) with virus/bacterium attached at the free end of cantilever through vibration analysis. Various viruses/bacteria having mass of the order of zeptogram level are considered for obtaining resonance frequencies of cantilevered triple-walled boron nitride nanotube (TW-BNNT) by means of a continuum mechanics-based analytical approach. The simulation with various viruses/bacteria attached at the tip of cantilevered TW-BNNT is carried out for different lengths. The finite element method simulated resonance frequency values are compared with results obtained from the analytical method by taking into account the effective wall thickness of tubes and van der Waals interaction between various BNNTs. A close proximity is observed between results obtained from the two approaches, which further confirms the validity of the proposed model. The obtained results suggest that shorter length TW-BNNT is more sensitive for detecting viruses/bacteria having mass of zeptogram order.
机译：本研究通过振动分析探索了使用病毒/细菌附着在悬臂自由端的多壁氮化硼纳米管（MW-BNNT）的生物传感器的适用性。为了通过基于连续力学的分析方法获得悬臂式三壁氮化硼纳米管（TW-BNNT）的共振频率，考虑了具有Zeptogram水平量级的各种病毒/细菌。对于不同的长度，执行了在悬臂TW-BNNT尖端附着各种病毒/细菌的模拟。考虑到管的有效壁厚和各种BNNT之间的范德华相互作用，将有限元方法模拟的共振频率值与分析方法获得的结果进行比较。从这两种方法获得的结果之间观察到非常接近，这进一步证实了所提出模型的有效性。获得的结果表明，较短长度的TW-BNNT对检测具有Z谱图质量的病毒/细菌更敏感。

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