Fifty years of B lymphocytes

Alexander D. Gitlin; Michel C. Nussenzweig

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Fifty years of B lymphocytes

机译：B淋巴细胞五十年

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When Max Dale Cooper joined Robert Good's laboratory at the University of Minnesota in Minneapolis in 1963, there were two camps in immunology. Neither was particularly fond of the other. At the time, the central question in immunology was how vertebrates tailor their defences to bacteria and viruses, whose chemical structures show nearly unlimited diversity. Within two years of joining Good's laboratory, Cooper had made a discovery about the cells that accomplish this task - lymphocytes - that proved essential to cracking the mystery, and ultimately to unifying the camps of his field.

机译：当马克斯·戴尔·库珀（Max Dale Cooper）于1963年加入明尼阿波利斯明尼苏达大学的罗伯特·古德（Robert Good）的实验室时，免疫学就有两个阵营。双方都不特别喜欢对方。当时，免疫学的中心问题是脊椎动物如何针对细菌和病毒调整防御能力，而细菌和病毒的化学结构显示出几乎无限的多样性。在加入古德实验室的两年之内，库珀发现了完成这项任务的细胞-淋巴细胞-被证明对于破解谜团，最终统一他的阵营至关重要。

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来源
《Nature》 |2015年第7533期|139-141|共3页
作者
Alexander D. Gitlin; Michel C. Nussenzweig;
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作者单位

Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional progmmme in New York City, New York, USA;

HHMI investigator at Rockefeller University in New York, New York, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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Fifty years of B lymphocytes

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