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Racing against viral evolution

机译:对抗病毒进化

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The H7N9 strain that ripped through Shanghai killing dozens last spring tested our capacity to understand new viruses and China's ability to contain an epidemic It was tragic-but through concerted efforts by health officials and researchers around the globe, a much worse scenario was averted. Such sustained, global efforts, rooted in a dynamic research network, have become crucial part of our efforts to avoid a pandemic. Yoshihiro Kawaoka's laboratory at the University ofTokyo is a vital hub in this global battle. Kawaoka has set himself a challenge: to understand, and ultimately predict, the pandemic potential of influenza viruses by picking them apart at the molecular level. "Unless we unravel the viral and cellular determinants and mechanisms that define disease severity and transmissibility, we will not be able to predict the pandemic potential of novel strains, which would allow us to implement countermeasures to curtail future pandemics," he says.
机译:去年春天在上海肆虐的H7N9毒株测试了我们了解新病毒的能力以及中国遏制流行病的能力。这是悲剧性的,但是通过全球卫生官员和研究人员的共同努力,避免了更糟的情况。扎根于一个动态研究网络的这种持续的全球努力已成为我们避免大流行的努力的关键部分。东京大学的川冈义广实验室是这场全球战争的重要枢纽。川冈向自己提出了一个挑战:通过在分子水平上进行区分来理解并最终预测流感病毒的大流行潜力。他说:“除非我们揭开定义疾病严重程度和传播性的病毒和细胞决定因素和机制,否则我们将无法预测新菌株的大流行潜力,这将使我们能够采取对策来遏制未来的大流行。”

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  • 来源
    《Nature》 |2013年第2013index期|37-37|共1页
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  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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