Pathogens put the pressure on

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Pathogens put the pressure on

机译：病原体施加压力

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Pathogens have driven genetic adaptation in humans more than climate or diet has. Matteo Fumagalli, now at the University of California, Berkeley, and his colleagues calculated the frequency of different genetic variants in more than 1,500 people across 55 populations. They then developed a statistical model to predict the distribution of these variants across the populations. The model incorporates three potential selective pressures on the human genome: climate, diet regimes and pathogen load. Genetic variation correlated most strongly with local pathogen diversity.

机译：病原菌对人类遗传适应的推动作用超过气候或饮食。现任加州大学伯克利分校的Matteo Fumagalli及其同事计算了55个人群中超过1,500人的不同遗传变异的频率。然后，他们建立了一个统计模型，以预测这些变异在人群中的分布。该模型包含了对人类基因组的三种潜在选择压力：气候，饮食习惯和病原体负荷。遗传变异与当地病原体多样性密切相关。

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《Nature》 |2011年第7376期|p.155|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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Pathogens put the pressure on

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