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Separate Ways

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Protein separation is a highly valued and indispensable step in the research process - the development of techniques and methods for protein purification has been an essential requirement for many of the advances made in biotechnology. The key to successful protein purification is to select the most appropriate techniques and efficient tools.rnBAC has introduced two new products to its CaptureSelect Antibody Toolbox. The rnCaptureSelect IgA and IgM affinity matrices offer unparalleled specificity and product purity in a one-step purification process. CaptureSelect Human IgA affinity matrix contains an affinity ligand that binds to a unique domain that is present on all subclasses of human IgA, with no cross reactivity with IgM or IgG. The CaptureSelect IgM affinity matrix contains an affinity ligand that is directed towards a unique domain that is present on both human and mouse IgM antibodies, and offers no cross-reactivity with human or mouse IgA or IgM. "The products in our CaptureSelect Antibody Toolbox range simplify and streamline the purification of antibodies in the lab," explains Mark ten Haaft, Director of Ligand Application at BAC.
机译:蛋白质分离是研究过程中非常重要且必不可少的步骤-蛋白质纯化技术和方法的开发一直是生物技术取得许多进步的基本要求。成功纯化蛋白质的关键是选择最合适的技术和高效的工具。rnBAC在其CaptureSelect Antibody Toolbox中引入了两种新产品。 rnCaptureSelect IgA和IgM亲和基质在一步纯化过程中提供了无与伦比的特异性和产物纯度。 CaptureSelect Human IgA亲和基质包含一种亲和配体,该亲和配体与存在于人IgA的所有亚类上的唯一域结合,且与IgM或IgG没有交叉反应。 CaptureSelect IgM亲和基质包含针对人和小鼠IgM抗体上均存在的唯一域的亲和配体,并且与人或小鼠IgA或IgM没有交叉反应。 BAC配体应用主管Mark ten Haaft解释说:“我们的CaptureSelect抗体工具箱系列中的产品简化并简化了实验室中抗体的纯化。”

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  • 来源
    《Nature》 |2008年第7198期|001136_01001136_02|共2页
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  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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