Feedback control of intercellular signalling in development

Matthew Freeman

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Feedback control of intercellular signalling in development

机译：发育中细胞间信号的反馈控制

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The intercellular communication that regulates cell fate during animal development must be precisely controlled to avoid dangerous errors. How is this achieved? Recent work has highlighted the importance of positive and negative feedback loops in the dynamic regulation of developmental signalling. These feedback interactions can impart precision, robustness and versatility to intercellular signals. Feedback failure can cause disease.

机译：必须精确控制调节动物发育过程中细胞命运的细胞间通讯，以避免危险的错误。如何实现的？最近的工作强调了正反馈回路和负反馈回路在发育信号的动态调节中的重要性。这些反馈相互作用可以赋予细胞间信号精确性，鲁棒性和多功能性。反馈失败会导致疾病。

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《Nature》 |2000年第6810期|p.313-319|共7页
作者
Matthew Freeman;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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Feedback control of intercellular signalling in development

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