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Peanut allergy cured a little at a time

机译:花生过敏一次治愈

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摘要

It was a tough nut to crack. But for the first time, children with a potentially lethal peanut allergy have essentially been cured using an oral immunotherapy. "We've shown fantastic results, with [over] 80 per cent of children being able to tolerate eating peanuts regularly after treatment," says Andrew Clark of Addenbrooke's Hospital in Cambridge, UK. Two per cent of children are allergic to peanuts, and around 50 people in the US die each yearf rom the allergy. The trial involved 99 children with a peanut allergy aged between 7 and 16. In a hospital setting, half of the children were given a tiny dose of peanut flour - around 2 milligrams -in their food once a day. The same amount was then added to their meals at home for the next two weeks. Then, over a six-month period, the daily peanut dose was ramped up every two weeks, each time at hospital, to reach 800 milligrams - the equivalent of five peanuts. A control group of 50 children received no therapy, and continued to avoid exposure to peanuts.
机译:这是一个很难破解的坚果。但是第一次,具有潜在致死性花生过敏症的儿童基本上已经通过口服免疫疗法治愈。 “我们显示出了惊人的效果,治疗后[超过] 80%的儿童能够忍受规律地食用花生,”英国剑桥阿登布鲁克医院的安德鲁·克拉克(Andrew Clark)说。 2%的儿童对花生过敏,美国每年约有50人死于过敏。该试验涉及99名7至16岁的花生过敏儿童。在医院,每天给他们的食物中的一半提供一小剂量的花生粉-约2毫克。然后在接下来的两个星期中,将相同数量的食物添加到他们的家里。然后,在六个月的时间里,每次在医院,每两周增加一次每日花生剂量,达到800毫克-相当于五个花生。对照组的50名儿童未接受任何治疗,并继续避免接触花生。

著录项

  • 来源
    《New scientist》 |2014年第2955期|14-14|共1页
  • 作者

    Andy Coghlan;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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