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首页> 外文期刊>Obesity Surgery >The Surgical Treatment of Type II Diabetes Mellitus: Changes in HOMA Insulin Resistance in the First Year Following Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and Laparoscopic Adjustable Gastric Banding (LAGB)
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The Surgical Treatment of Type II Diabetes Mellitus: Changes in HOMA Insulin Resistance in the First Year Following Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and Laparoscopic Adjustable Gastric Banding (LAGB)

机译:II型糖尿病的外科治疗:腹腔镜Roux-en-Y胃旁路术(LRYGB)和腹腔镜可调胃绑扎术(LAGB)后第一年HOMA胰岛素抵抗的变化

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摘要

Bariatric operations significantly improve glucose metabolism, decrease insulin resistance, and lead to clinical resolution of type II diabetes mellitus in many patients. The mechanisms that achieve these clinical outcomes, however, remain ill defined. Moreover, the relative impact of various operations on insulin resistance remains vigorously contested. Consequently, the purpose of this study was to compare directly the impact of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB) on hemoglobin A1c (HbA1c) levels and insulin resistance in comparable groups of morbidly obese patients.
机译:减肥手术显着改善了葡萄糖代谢,降低了胰岛素抵抗,并导致许多患者Ⅱ型糖尿病的临床解决。然而,实现这些临床结果的机制仍然不清楚。此外,各种操作对胰岛素抵抗的相对影响仍在激烈争论。因此,本研究的目的是直接比较腹腔镜Roux-en-Y胃搭桥术(LRYGB)和腹腔镜可调节胃绑带(LAGB)对可比的病态肥胖患者血红蛋白A1c(HbA1c)水平和胰岛素抵抗的影响。

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