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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Pemphigus vulgaris induced by 5-aminolaevulinic acid-based photodynamic therapy
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Pemphigus vulgaris induced by 5-aminolaevulinic acid-based photodynamic therapy

机译：基于5-氨基松油酸的光动力疗法诱导寻常型天疱疮

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摘要

Pemphigus vulgaris (PV) is an autoimmune disorder resulting from the interaction between autoantibodies and desmoglein. Here, we report a case of PV developed after 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT). The harmful and deleterious effects of UV radiation on the onset, during course, and perpetuation of PV have been observed for decades. Correlation between reactive oxygen species (ROS) and PV have also been reported. Oxidative proteins, which are modified by ROS, and subsequent production of antibodies by immune system seem to be responsible for PV developed following ALA-PDT. We emphasize that ALA-PDT should be added to the list of possible factors triggering PV and this condition should be considered if blistering arises following ALA-PDT.
机译：寻常型天疱疮（PV）是由于自身抗体与桥粒芯蛋白之间的相互作用而引起的自身免疫性疾病。在这里，我们报告一例基于5-氨基松油酸的光动力疗法（ALA-PDT）后发展的PV。数十年来，人们一直观察到紫外线辐射对PV的发作，过程和永存的有害影响。还已经报道了活性氧（ROS）与PV之间的相关性。被ROS修饰的氧化蛋白以及随后由免疫系统产生的抗体似乎是导致ALA-PDT产生的PV的原因。我们强调，应将ALA-PDT添加到触发PV的可能因素列表中，如果在ALA-PDT之后出现起泡，则应考虑这种情况。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2017年第9期|156-158|共3页
  • 作者

    Zhou Qian; Wang Peiru; Zhang Linglin; Wang Bo; Shi Lei; Keyal Uma; Bhatta Anil Kumar; Zhang Guolong; Wang Xiuli;

  • 作者单位

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

    Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China;

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  • 正文语种 eng
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  • 关键词

    Photodynamic therapy; Pemphigus vulgaris; Basal cell carcinoma; Reactive oxygen species;

    机译：光动力疗法寻常型天疱疮基底细胞癌活性氧;

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