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Photodynamic therapy (PDT) for lung cancer

机译:肺癌的光动力疗法(PDT)

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摘要

Clinical PDT began in the early 1980s and lung cancer was one of the first indications for which the procedure was tried. Initially patients with advanced inoperable cancer and major bronchial obstruction were targeted with the objective of relief of airway obstruction and symptom palliation.In the past 30 years, assisted by progress in imaging methods and advances of technologi-cal developments, PDT indications have expanded to incorporate a multitude of lung cancer presentations which this review aims to display.Locally advanced and early stage endobronchial cancer continues to be the major indications albeit with a more precise diagnostic and guided Hlumination devices. Peripheral parenchy-mal disease has been a technical challenge but there is still ongoing development. Multifocal synchronous, recurrence and metachronous endobronchial disease following lung resection are now an up and coming indication with rewarding outcome. More importantly PDTs role within a multi-disciplinary assautt on lung cancer is receiving acceptance.
机译:临床PDT始于1980年代初期,肺癌是尝试该方法的最早适应症之一。最初以晚期无法手术治疗的癌症和严重支气管阻塞的患者为目标,以缓解气道阻塞和症状减轻。在过去的30年中,随着影像学方法的进步和技术发展的进步,PDT适应症已扩大到纳入本综述旨在展示多种肺癌表现。局部晚期和早期支气管内癌仍是主要适应症,尽管采用了更精确的诊断和引导性消融装置。周围实质性疾病一直是一项技术挑战,但仍在持续发展中。肺切除术后多灶同步性,复发性和异时性支气管内疾病现已成为一种可喜的结果,其预后良好。更重要的是,PDT在肺癌的多学科评估中的作用正在被接受。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2011年第3期|p.231-239|共9页
  • 作者单位

    21st Century Oncology, 801 WH Smith Blvd, GreenvUle, NC 27834, USA;

    rnYorkshire Laser Centre, Coole DN14 6RX, UK Hutt & East Yorkshire NHS Trust, UK North Lincolnshire & Goole Hospitals NHS Trust, UK;

    rnNortheast Texas Interventional Medicine, 301 W 18th St Ste 101, Mount Pleasant, TX, USA;

    rnYorkshire Laser Centre, Coole DN14 6RX, UK;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    PDT; Lung cancer;

    机译:太平洋夏令时;肺癌;

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