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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Perspective clinical study on effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating condylomata acuminata in pregnancy
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Perspective clinical study on effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating condylomata acuminata in pregnancy

机译：5-氨基乙酰丙酸光动力疗法（ALA-PDT）治疗妊娠期尖锐湿疣疗效的前瞻性临床研究

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摘要

Objective: To observe the clinical efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating vulval condylomata acuminata (CA) in pregnancy.Methods: The clinical efficacies of ALA-PDT on 16 cases of CA in pregnancy as well as cryotherapy on 22 cases of CA in pregnancy were analyzed in this prospective study.Results: The treatment group showed a wart clearance rate of 93.8% after 3 PDT treatments, while the control group showed a wart clearance rate of 72.7% after 3 cryotherapy treatments. After the 3-month follow-up period, the treatment group registered a recurrence rate of 6.3%, whereas the control group recorded a recurrence rate of 36.4%, indicating a statistically significant difference (chi(2) = 4.674, p = 0.031 0.05). After the 1-month postpartum follow-up period, the newborns grew and developed well, without any abnormality in physical examinations.Conclusion: ALA-PDT is safe and effective in treating CA in pregnancy.
机译：目的：观察5-氨基乙酰丙酸光动力疗法（ALA-PDT）治疗妊娠期外阴尖锐湿疣（CA）的方法。方法：ALA-PDT对16例妊娠期CA的临床疗效及冷冻疗法结果：治疗组3次PDT治疗后疣清除率达93.8％，对照组3次冷冻治疗后疣清除率达72.7％。在3个月的随访期之后，治疗组的复发率为6.3％，而对照组的复发率为36.4％，表明具有统计学显着性差异（chi（2）= 4.674，p = 0.031 < 0.05）。产后1个月的随访后，新生儿生长发育良好，体格检查无异常。结论：ALA-PDT是安全有效的妊娠CA治疗方法。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2019年第3期|63-65|共3页
  • 作者

    Yang Yuguang; Zhang Yunjie; Zou Xianbiao; Guo Xiaojuan; Lin Hui;

  • 作者单位

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

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  • 正文语种 eng
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  • 关键词

    Condylomata acuminata (CA); Photodynamic therapy (PDT); Pregnancy; Cryotherapy;

    机译：尖锐湿疣（CA）;光动力疗法（PDT）;妊娠;冷冻疗法;

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