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Plum-blossom needle assisted photodynamic therapy for the treatment of oral potentially malignant disorder in the elderly

机译:梅花针辅助光动力疗法治疗老年人口腔潜在恶性疾病

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摘要

Oral leukoplakia (OLK) is one of the most common oral potentially-malignant disorders (OPMD) with complex causes, a long disease course and a high tendency for recrudescence. Although a variety of methods exist for treating this disease, canceration rates remain high. Herein, we described a case of 72-year-old male patient with OLK of the palatine mucous membrane who had achieved complete remission after being treated with five sessions of plum-blossom needle (PBN) assisted 5-aminolevulinic acid-photodynamic therapy (ALA-PDT). The patient had since been subsequently placed under close observation ( 12 mo). To date, there has been no recurrence. PBN assisted PDT might be suitable for the treatment of OPMDs in patients presenting with epithelial hyperkeratosis.
机译:口腔白斑(OLK)是最常见的口腔潜在恶性疾病(OPMD),其病因复杂,病程长,复发倾向高。尽管存在多种用于治疗该疾病的方法,但是癌变率仍然很高。本文中,我们描述了一例72岁的男性with肌黏膜OLK患者,该患者在接受五次梅花针(PBN)辅助5-氨基乙酰丙酸光动力疗法(ALA)治疗后已完全缓解-太平洋夏令时)。此后,患者被严密观察(> 12 mo)。迄今为止,还没有复发。 PBN辅助的PDT可能适合治疗上皮角化过度的患者的OPMD。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2019年第3期|296-299|共4页
  • 作者单位

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

    Peking Univ, Dept Oral Med, Sch & Hosp Stomatol, 22 Zhongguancun South Ave, Beijing 100081, Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Oral potentially-malignant disorders; Oral leukoplakia; Hyperkeratosis; Plum-blossom needle; Photodynamic therapy; Aminolevulinic acid;

    机译:口腔潜在恶性疾病;口腔白斑;角化过度;梅花针;光动力疗法;氨基乙酰丙酸;

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