• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Clinical periodontal, bacterial, and immunological outcomes of antimicrobial photodynamic therapy in orthodontic treatment-induced gingival enlargement
【24h】

Clinical periodontal, bacterial, and immunological outcomes of antimicrobial photodynamic therapy in orthodontic treatment-induced gingival enlargement

机译：正畸治疗诱导的牙龈扩大术抗微生物光动力治疗的临床牙周病，细菌和免疫结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Aim: The aim of the present clinical trial is to evaluate the clinical, bacterial, and immunological outcomes of photodynamic therapy (PDT) in adolescent patients with orthodontic treatment-induced gingival enlargement (OTGE).Materials and methods: A total of 26 adolescent patients, 16 girls and 10 boys, of mean age 16.8 years, undergoing fixed orthodontic treatment for at least 6 months (mean duration in months, 8.3 +/- 1.9) and presenting with GE were included in the clinical trial. All patients undergoing fixed orthodontic treatment with clinical diagnosis of OTGE were divided into two groups: Patients receiving full-mouth periodontal debridement (FMPD) 'Group-FMPD' and 'Group-PDT' included participants receiving methylene blue-assisted PDT in the selected area along with FMPD. Clinical periodontal assessments included the evaluation of plaque scores (PS), bleeding on probing (BOP), probing depth (PD) and hyperplastic index (HI). The total bacterial counts of Porphyromonas gingivalis (P. gingivalis), Treponema denticola (T. denticola), and Tannerella forsythia (T. forsythia) were estimated and expressed as log CFU/mL of each bacteria. Cytokines including interleukin (IL)-1 beta and IL-6 were analyzed using enzyme-linked immunosorbent assay (ELISA) kit.Results: The mean percentage of PS and BOP statistically significantly reduced with both FMPD and PDT from baseline to 4 weeks (p 0.05). Although mean PD significantly reduced in both the groups at all time points, there was significantly higher reduction with PDT as compared to FMPD M 2 weeks post treatment (p 0.05). Inter-group comparison showed PDT demonstrated significantly higher HI M 2- and 4-weeks post treatment (p 0.05). The mean log CFU/mL of P. gingivalis and T. forsythia showed statistically significantly higher reduction with PDT than FMPD (p 0.05) M both 2-and 4-weeks follow-up. T. denticola reported significantly reduced levels at 2 weeks follow-up period only with PDT (p 0.05). No statistically significant difference appeared when both treatment modalities were compared with one another (p 0.05). Four weeks after periodontal treatment, IL-6 significantly reduced with PDT compared to FMPD (p 0.05).Conclusion: PDT assisted in reducing bacterial counts and improving hyperplastic index in OTGE.
机译：目的：目前临床试验的目的是评估青少年治疗诱导的牙龈增大（OTGE）的青少年患者光动力治疗（PDT）的临床，细菌和免疫结果。材料和方法：共有26例青少年患者16例女孩和10名男孩，平均年龄为16.8岁，经历固定的正畸治疗至少6个月（在数月，8.3 +/- 1.9）和用GE呈现，临床试验。所有接受临床诊断的固定正畸治疗的患者分为两组：接受全口牙周清创（FMPD）'Grous-FMPD'和“​​Group-PDT”的患者包括接受所选区域中的亚甲基蓝辅PDT的参与者以及fmpd。临床牙周期评估包括斑块评分（PS）的评估，探测（BOP），探测深度（PD）和增生指数（HI）上出血。估计卟啉核苷酸（P.Gingivalis），TheNnerella牙科拉（T.Denticola）和坦恩斯菌的总细菌计数，并表达每种细菌的Log Cfu / ml。使用酶联免疫吸附测定（ELISA）试剂术分析包括白细胞介素（IL）-1β和IL-6的细胞因子：结果：PS和BOP的平均百分比与FMPD和PDT统计学显着减少到基线至4周（P <0.05）。虽然在所有时间点的两组中的平均值显着降低，但与处理后的FMPD M 2周相比，PDT显着降低了（P <0.05）。群体间比较显示PDT在治疗后HI M 2和4周的均显着更高（P <0.05）。 P.Gingivalis和T.连续性的平均原木CFU / ml表现出统计学上显着更高，PDT减少而不是FMPD（P <0.05）M两次和4周随访。 T.Denticola报告仅用PDT的2周随访期间显着降低（P <0.05）。当两个治疗方式彼此进行比较时，不会出现统计学上显着的差异（p> 0.05）。牙周治疗后四周，与FMPD相比，IL-6与PDT显着降低（P <0.05）。结论：PDT辅助降低细菌计数并改善OTGE中的增生指数。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号