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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Evaluation of choroidal thickness and retinal vessel density in patients with inactive Graves' orbitopathy
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Evaluation of choroidal thickness and retinal vessel density in patients with inactive Graves' orbitopathy

机译：非活动坟墓胰腺炎患者脉络膜厚度和视网膜密度的评价

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Background: To investigate choroidal thickness using spectral domain-optical coherence tomography and retinal vessel density with optical coherence tomography angiography in patients with inactive Graves' orbitopathy.Methods: A total of 36 eyes of 36 patients with inactive Graves' orbitopathy (6 men and 30 women in Group 1) and 36 eyes from 36 controls (8 men and 28 women in Group 2) were recruited for this prospective case-control study. Choroidal thickness measurements were obtained using enhanced depth imaging with spectral domainoptical coherence tomography. Optical coherence tomography angiography images were generated with 6 x 6mm angiographic optical coherence tomography scans. Retinal vessel densities of the superficial retinal layer and deep retinal layer of the macula and foveal avascular zone measurements were obtained for each eye.Results: The mean age was 42.5 +/- 9.9 years in Group 1 and 42.8 +/- 6.5 years in Group 2 (p = 0.76). The mean choroidal thickness was 370.7 +/- 83.5 mu m and 338.2 +/- 72.4 mu m in Group 1 and 2, respectively (p = 0.09). There was no significant difference between the groups in retinal vessel density either in superficial or deep retinal layers (p 0.05 for all), and no difference was found between the groups in foveal avascular zone area and perimeter (p = 0.69, p = 0.73, respectively).Conclusions: Similar retinal vessel density values were found in both superficial and deep retinal layers in Graves' orbitopathy compared with healthy subjects. Although statistically insignificant, choroidal thickness was slightly higher in patients with Graves' orbitopathy than in healthy subjects. Foveal avascular zone area and perimeter measurements were unaffected by the disease.
机译：背景：使用光谱域 - 光学相干断层扫描和视网膜血管密度来研究脉络膜厚度，具有无活性坟墓的患者光学相干断层造影血管造影。方法：共有36名36名患者的36名无活性坟墓胰腺炎（6名男子和30名第1组的妇女，36只眼睛从36个控制（第2组中的8名男子和28名女性）被招募了这项前瞻性案件对照研究。使用具有光谱导致相干断层扫描的增强深度成像获得脉络膜厚度测量。使用6×6mm血管造影光学相干断层扫描产生光学相干断层造影血管造影图像。为每只眼睛获得浅表视网膜层和黄斑和血管缺血区测量的视网膜血管密度。结果：第1次和42.8 + 42.8 +/- 6.5岁的平均年龄为42.5 +/- 9.9岁2（p = 0.76）。平均脉络膜厚度为370.7 +/-83.5μm和338.2 +/-72.4μm，分别为1和2组（p = 0.09）。视网膜血管密度的基团之间没有显着差异，无论是浅表或深视网膜层（全部p> 0.05），在血糖缺血区区域和周边的组之间没有发现差异（p = 0.69，p = 0.73分别为较健康的受试者，分别在Graves胰腺病患中的浅表和深视网膜层中发现了类似的视网膜血管密度值。虽然统计学上微不足道，但在坟墓胰腺病的患者中脉络膜厚度略高于健康受试者。心脏缺血区区域和周边测量不受该疾病的影响。

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