...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Potato Research >Potato Steroidal Glycoalkaloids: Biosynthesis and Genetic Manipulation
【24h】

Potato Steroidal Glycoalkaloids: Biosynthesis and Genetic Manipulation

机译：马铃薯甾体类生物碱：生物合成和遗传操纵。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The potato steroidal glycoalkaloids (SGAs) are important components of plant resistance against pests and pathogens but can be toxic to humans at high levels. SGAs derive their toxicity from anticholinesterase activity affecting the central nervous system and the disruptive effects on cell membrane integrity affecting the digestive system and other organs. Accordingly, current safety regulations limit their content in the edible tuber to 20 mg per 100 g fresh weight. SGA composition and level are genetically determined, with unfavourable growth conditions and inappropriate postharvest management inducing the accumulation of SGAs at levels in the tubers of “safe” cultivars beyond the maximum level set by the industry. Hence, genetic alteration of potato to prevent toxic levels of SGAs in tubers is highly desirable. At the same time, maintaining high SGA levels in other plant organs will contribute to plant resistance against pathogen and pest attacks. To this end, SGA biosynthesis and degradation should be manipulated precisely to exploit tissue-specific expression rather than whole-plant suppression of SGA production, to produce potato cultivars with SGA content enriched in the foliage but diminished in the edible tubers. Only a few details are known about the SGA biosynthetic pathway, its genes and intermediates. Research on factors that regulate SGA biosynthesis and catabolism as well as searches for genetic markers linked to total and specific SGA levels have only recently been pursued. The present review summarizes current data on these issues to encourage further discussion on SGA manipulation for safer food products. Keywords Chaconine - Diversity - Leptines - Solanine - Solanum tuberosum
机译：马铃薯甾体类生物碱（SGAs）是植物抵抗病虫害和病原体的重要组成部分，但对人体有高水平的毒性。 SGA的毒性来自抗胆碱酯酶活性，影响中枢神经系统，破坏细胞膜完整性，影响消化系统和其他器官。因此，当前的安全法规将其在食用块茎中的含量限制为每100克鲜重20毫克。 SGA的组成和水平是由遗传决定的，不利的生长条件和不适当的收获后管理导致“安全”品种块茎中SGA的积累水平超过了行业设定的最高水平。因此，非常需要对马铃薯进行遗传改造以防止块茎中SGA的毒性水平。同时，在其他植物器官中保持较高的SGA水平将有助于植物抵抗病原体和害虫。为此，应该精确地控制SGA的生物合成和降解，以利用组织特异性表达，而不是整个植物抑制SGA的产生，以生产马铃薯SGA含量高，但在食用块茎中含量降低的马铃薯品种。关于SGA生物合成途径，其基因和中间体的信息很少。直到最近才对调节SGA生物合成和分解代谢的因子进行研究，以及寻找与总SGA水平和特定SGA水平相关的遗传标记。本综述总结了有关这些问题的最新数据，以鼓励就更安全的食品使用SGA进行进一步的讨论。关键词查茄碱-多样性-瘦素-茄碱-马铃薯

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号