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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >An unusual histone H3 specific for early macronuclear development in Euplotes crassus
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An unusual histone H3 specific for early macronuclear development in Euplotes crassus

机译:一种不寻常的组蛋白H3,特异于Euplotes crassus的早期大核发育

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摘要

Characterization of the histone H3 genes of the ciliated protozoan Euplotes crassus indicates that one gene functions only during the sexual phase of the life cycle. Maximum expression of this gene, as judged by transcript accumulation, correlates with DNA replications leading to polytenization of the micronuclear chromosomes before mas- sive DNA elimination, which produces a transcriptionally active macronucleus. Transcripts of the other gene accumu- late primarily during vegetative growth and in the sexual phase of the life cycle during replication phases not related to polytenization.
机译:纤毛原生动物Eupplotes crassus的组蛋白H3基因的特征表明,一个基因仅在生命周期的性阶段起作用。根据转录物的积累判断,该基因的最大表达与DNA复制有关,从而导致大量DNA消除之前微核染色体的多聚化,从而产生了具有转录活性的大核。其他基因的转录本主要在营养生长期间以及在与多态化无关的复制阶段的生命周期性阶段积累。

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