Genetic ablation of parietal cells in transgenic mice: A new model for analyzing cell lineage relationships in the gastric mucosa

Victor Canfield; A. Brian West; James R. Goldenring

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Genetic ablation of parietal cells in transgenic mice: A new model for analyzing cell lineage relationships in the gastric mucosa

【24h】

Genetic ablation of parietal cells in transgenic mice: A new model for analyzing cell lineage relationships in the gastric mucosa

机译：转基因小鼠壁细胞的遗传消融：分析胃粘膜细胞谱系关系的新模型

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The gastric mucosa of mammalian stomach contains several differentiated cell types specialized for the secretion of acid, digestive enzymes, mucus, and hormones. Understanding whether each of these cell lineages is derived from a common stem cell has been a challenging problem. We have used a genetic approach to analyze the ontogeny of progenitor cells within mouse stomach.

机译：哺乳动物胃的胃粘膜含有几种分化的细胞类型，专门用于分泌酸，消化酶，粘液和激素。了解这些细胞谱系中的每个谱系是否源自共同的干细胞一直是一个具有挑战性的问题。我们已经使用一种遗传方法来分析小鼠胃内祖细胞的发生。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第6期|p.2431-2435|共5页
作者
Victor Canfield; A. Brian West; James R. Goldenring;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages [J] . Youichi Miyaoka, Yasunori Kadowaki, Shunji Ishihara, Oncogene . 2004,第20期

机译：Reg蛋白的转基因过表达引起胃细胞增殖和沿着椎管细胞和主要细胞谱系的分化
2. Establishment of a gastric epithelial progenitor cell line from a transgenic mouse expressing the simian virus 40 large T antigen gene in the parietal cell lineage. [J] . Farook VS, Alkhalaf M, Karam SM Cell Proliferation . 2008,第2期

机译：从在顶细胞谱系中表达猿猴病毒40大T抗原基因的转基因小鼠建立胃上皮祖细胞系。
3. Ultrastructural transformation of gastric parietal cells reverting from the active to the resting state of acid secretion revealed in isolated rat gastric mucosa model processed by high-pressure freezing. [J] . Sawaguchi A, Aoyama F, Ohashi M, Journal of Electron Microscopy . 2006,第2期

机译：在高压冷冻处理的分离的大鼠胃粘膜模型中揭示了胃壁细胞的超微结构转化，从酸性分泌的活跃状态恢复到静止状态。
4. Establishment of a ghrelin-produeing cell line from a gastric tumor in ghrelin-promoter SV40 T-antigen transgenic mice [C] . Hiroshi lwakura, Yushu Li, Hiroshi Hosoda Japanese peptide symposium . 2011

机译：从Ghrelin-Lightors SV40 T-抗原转基因小鼠中胃肿瘤建立Ghrelin-Produe细胞系
5. Genetic ablation of the platelet activating factor receptor does not impair learning and memory in wild-type mice or alter amyloid plaque number in a transgenic model of Alzheimer's disease [D] . Peshdary, Vian. 2012

机译：血小板活化因子受体的遗传消融不会损害野生型小鼠的学习和记忆，也不会改变阿尔茨海默氏病转基因模型中的淀粉样斑块数
6. Genetic ablation of parietal cells in transgenic mice: a new model for analyzing cell lineage relationships in the gastric mucosa. [O] . V Canfield, A B West, J R Goldenring, 1996

机译：转基因小鼠壁细胞的遗传消融：一种用于分析胃粘膜细胞谱系关系的新模型。
7. Genetic ablation of parietal cells in transgenic mice: a new model for analyzing cell lineage relationships in the gastric mucosa. [O] . Canfield, V, West, A B, Goldenring, J R, 1996

机译：转基因小鼠壁细胞的遗传消融：一种用于分析胃粘膜细胞谱系关系的新模型。
8. Ultrastructural changes of the parietal cell in the ferret gastric mucosa induced by pylorus-ligation and glucocorticoid administration [R] . Pfeiffer, C. J., Stephens, R. J. 1967

机译：幽门结扎和糖皮质激素诱导鼬胃粘膜壁细胞超微结构的变化

Genetic ablation of parietal cells in transgenic mice: A new model for analyzing cell lineage relationships in the gastric mucosa

摘要

著录项

相似文献

相关主题

期刊订阅