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The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation

机译:酵母ZRT1基因编码由锌限制诱导的高亲和吸收系统的锌转运蛋白

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摘要

The yeast Saccharomyces cerevisiae has two separate systems for zinc uptake. One system has high affinity for substrate and is induced in zinc-deficient cells. The second system has lower affinity and is not highly regulated by zinc status. The ZRT1 gene encodes the transporter for the high- affinity system, called Zrt1p. The predicted amino acid se- quence of Zrt1p is similar to that of Irt1p, a probable Fe(II) transporter from Arabidopsis thaliana. Like Irt1p, Zrt1p con- tains eight potential transmembrane domains and a possible metal-binding domain.
机译:酵母酿酒酵母具有两个单独的锌吸收系统。一种系统对底物具有高亲和力,并在缺锌细胞中被诱导。第二种系统具有较低的亲和力,并且不受锌状态的高度调节。 ZRT1基因编码称为Zrt1p的高亲和力系统的转运蛋白。 Zrt1p的预测氨基酸序列与拟南芥中可能的Fe(II)转运蛋白Irt1p的序列相似。与Irt1p一样,Zrt1p包含八个潜在的跨膜结构域和可能的金属结合结构域。

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