Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

A. H. Gazzaley; S. J. Siegel; J. H. Kordower

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Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

机译：老年猴齿状回中N-甲基-D-天冬氨酸受体亚基1的电路特异性改变

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摘要

Age-associated memory impairment occurs frequently in primates. Based on the established importance of both the perforant path and N-methyl-D-aspartate (NMDA) receptors in memory formation, we investigated the glutamate receptor distribution and immunofluorescence intensity within the dentate gyrus of juvenile, adult, and aged macaque monkeys with the combined use of subunit-specific antibodies and quantitative confocal laser scanning microscopy.

机译：与年龄相关的记忆障碍经常发生在灵长类动物中。基于既定的穿孔途径和N-甲基-D-天冬氨酸（NMDA）受体在记忆形成中的重要性，我们调查了幼年，成年和成年猕猴的齿状回中谷氨酸受体的分布和免疫荧光强度。结合使用亚单位特异性抗体和定量共聚焦激光扫描显微镜。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3121-3125|共5页
作者
A. H. Gazzaley; S. J. Siegel; J. H. Kordower;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. N-methyl-D-aspartate receptor subunit 1 regulates neurogenesis in the hippocampal dentate gyrus of schizophrenia-like mice [J] . Juan Ding, Chun Zhang, Yi-Wei Zhang, Neural regeneration research . 2019,第12期

机译：N-甲基-D-天冬氨酸受体亚基1调节精神分裂症样小鼠海马齿状回的神经发生。
2. N-methyl-D-aspartate receptor subunit 1 regulates neurogenesis in the hippocampal dentate gyrus of schizophrenia-like mice [J] . Juan Ding, Chun Zhang, Yi-Wei Zhang, Neural regeneration research . 2019,第12期

机译：N-甲基-D-天冬氨酸受体亚基1调节精神分裂症样小鼠海马齿状回的神经发生。
3. Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo [J] . Kobi Rosenblum, Yadin Dudai, Gal Richter-Levin Proceedings of the National Academy of Sciences of the United States of America . 1996,第19期

机译：长期增强增强大鼠齿状回体内N-甲基-D-天冬氨酸受体亚基2B的酪氨酸磷酸化
4. The selective antagonism of A2A adenosine receptors prevents synaptic failure induced by oxygen and glucose deprivation in rat dentate gyrus [C] . Maraulaa G., Trainia C., Mellob T., European Congress of Pharmacology . 2012

机译：A2A腺苷受体的选择性拮抗剂可防止氧气牙齿诱导的氧气失败和葡萄糖剥夺的突触失败
5. Effects of ghrelin receptor knockout and age on spatial learning, neurogenesis, and spine density in the dentate gyrus of rats. [D] . Cahill, Shaina P A. 2013

机译：生长激素释放肽受体敲除和年龄对大鼠齿状回空间学习，神经发生和脊柱密度的影响。
6. Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys. [O] . A H Gazzaley, S J Siegel, J H Kordower, 1996

机译：老年猴齿状回中N-甲基-D-天冬氨酸受体亚基1的电路特异性变化。
7. Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys. [O] . Gazzaley, A H, Siegel, S J, Kordower, J H, 1996

机译：老年猴齿状回中N-甲基-D-天冬氨酸受体亚基1的电路特异性改变。
8. Modulation of Long-Term Potentiation and Epileptiform Activity in the Rat Dentate Gyrus by the Group II Metabotropic Glutamate Receptor Subtype mGluR3 [R] . Lea, P. M. 2000

机译：II组代谢型谷氨酸受体亚型mGluR3对大鼠齿状回长期增强和癫痫样活动的调节

Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

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