RecA protein stimulates homologous recombination in plants

Bernd Reiss; Manfred Klemm; Hans Kosak

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RecA protein stimulates homologous recombination in plants

机译：RecA蛋白刺激植物中的同源重组

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A number of RecA-like proteins have been found in eukaryotic organisms. We demonstrate that the prokaryotic recombination protein RecA itself is capable of interacting with genomic homologous DNA in somatic plant cells. Resistance to the DNA crosslinking agent mitomycin C requires homologous recombination as well as excision repair activity. Tobacco protoplasts expressing a nucleus-targeted RecA protein were at least three times as efficient as wild-type cells in repairing mitomycin C-induced damage.

机译：在真核生物中发现了许多类似RecA的蛋白质。我们证明原核重组蛋白RecA本身能够与体植物细胞中的基因组同源DNA相互作用。对DNA交联剂丝裂霉素C的抗性需要同源重组以及切除修复活性。表达核靶向RecA蛋白的烟草原生质体在修复丝裂霉素C诱导的损伤方面的效率至少是野生型细胞的三倍。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3094-3098|共5页
作者
Bernd Reiss; Manfred Klemm; Hans Kosak;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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专利

1. Overexpression of bacterial RecA protein stimulates homologous recombination in somatic mammalian cells. [J] . Shcherbakova OG, Lanzov VA, Ogawa H, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2000,第1期

机译：细菌RecA蛋白的过度表达会刺激哺乳动物体细胞中的同源重组。
2. Investigation of mycobacterial recA function: protein introns in the RecA of pathogenic mycobacteria do not affect competency for homologous recombination. [J] . Frischkorn K, Sander P, Scholz M, Molecular Microbiology . 1998,第5期

机译：分枝杆菌recA功能的研究：致病性分枝杆菌的RecA中的蛋白质内含子不影响同源重组的能力。
3. Characterization of a Mutant RecA Protein that Facilitates Homologous Genetic Recombination but not Recombinational DNA Repair: RecA423 [J] . Koichiro Ishimori, Suzanne Sommer, Adriana Bailone, Journal of Molecular Biology . 1996,第4期

机译：可促进同源基因重组但不能重组DNA修复的突变RecA蛋白的表征：RecA423
4. Comparative genomics revealed a novel DNA-binding regulatory protein involved in homologous recombination in bacteria [C] . Yang Gao, Yan Zhang 2011 IEEE International Conference on Systems Biology . 2011

机译：比较基因组学揭示了一种新型的DNA结合调节蛋白，参与细菌的同源重组
5. DNA recombination in plant mitochondria: Identification and functional analysis of a mitochondrial targeted homologue of a bacterial RecA protein in Arabidopsis thaliana. [D] . Khazi, Fayaz Ahmed Rahmatulla. 2002

机译：植物线粒体中的DNA重组：拟南芥中细菌RecA蛋白的线粒体靶向同源物的鉴定和功能分析。
6. RecA protein stimulates homologous recombination in plants. [O] . B Reiss, M Klemm, H Kosak, 1996

机译：RecA蛋白刺激植物中的同源重组。
7. RecA protein stimulates homologous recombination in plants. [O] . Reiss, B, Klemm, M, Kosak, H, 1996

机译：RecA蛋白刺激植物中的同源重组。
8. Characterization of the 'Pseudomonas aeruginosa recA' Analog and Its Protein Product: 'rec-102' is a Mutant Allele of the 'P. aeruginosa' PAO 'recA' Gene [R] . Kokjohn, T. A. , Miller, R. V. 1987

机译：'铜绿假单胞菌reca'类似物及其蛋白质产物的表征：'rec-102'是'p'的突变等位基因。铜绿假单胞菌'paO'reca'基因

RecA protein stimulates homologous recombination in plants

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