The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded β-sheets

Yoichi Kato; Takanori Muto; Takafumi Tomura

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The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded β-sheets

机译：人糖基化抑制因子的晶体结构是具有三个6链β-折叠的三聚体桶

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Glycosylation-inhibiting factor (GIF) is a cytokine that is involved in the regulation of IgE synthesis. The crystal structure of recombinant human GIF was determined by the multiple isomorphous replacement method. The struc- ture was refined to an R factor of 0.168 at 1.9 A deg resolution. The overall structure is seen to consist of three interconnected subunits forming a barrel with three 6-strandedβ-sheets on the inside and six -helices on the outside.

机译：糖基化抑制因子（GIF）是一种细胞因子，参与IgE合成的调控。重组人GIF的晶体结构是通过多重同构置换法确定的。在1.9 A deg分辨率下，该结构被精修到R系数为0.168。整体结构由三个相互连接的亚基组成，形成一个桶，桶的内部为三个6链β-折叠，外部为六个螺旋。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3007-3010|共4页
作者
Yoichi Kato; Takanori Muto; Takafumi Tomura;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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6. The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded beta-sheets. [O] . Y Kato, T Muto, T Tomura, 1996

机译：人糖基化抑制因子的晶体结构是具有三个6链β-折叠的三聚体桶。
7. The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded beta-sheets. [O] . Kato, Y, Muto, T, Tomura, T, 1996

机译：人糖基化抑制因子的晶体结构是具有三个6链β-折叠的三聚体桶。

The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded β-sheets

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