A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program

Krista M. Giglio; Nora Caberoy; Garret Suen; Dale Kaiser; Anthony G. Garza

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A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program

机译：一连串的增强调节剂结合蛋白启动并传播了多细胞发育程序

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Multicellular development is a trait often associated with eukaryotes, but it has become apparent in recent years that many, if not most bacterial species have the capacity for multicellular development when they reside in an appropriate natural environment. Bacterial development yields a remarkable array of complex multicellular forms. Some forms of multicellularity are ecologically important, such as the nitrogen-fixing heterocysts produced by certain species of photosynthetic cyanobacteria. Other forms of multicellularity are medically important, such as the pathogenic biofilms produced by Pseudomonas aeruginosa.

机译：多细胞发育是经常与真核生物相关的特征，但是近年来已经变得很明显，即使不是大多数细菌，如果存在于适当的自然环境中，许多细菌也具有多细胞发育的能力。细菌发育产生了一系列复杂的多细胞形式。某些形式的多细胞性在生态上很重要，例如某些光合作用蓝细菌产生的固氮异孢子虫。其他形式的多细胞性在医学上也很重要，例如铜绿假单胞菌产生的致病性生物膜。

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来源
《Proceedings of the National Academy of Sciences of the United States of America》 |2011年第32期|p.12981-12982|共2页
作者
Krista M. Giglio; Nora Caberoy; Garret Suen; Dale Kaiser; Anthony G. Garza;
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作者单位

Department of Biology, Syracuse University, Syracuse, NY 13244;

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL 33136;

Department of Bacteriology, University of Wisconsin-Madison, Madison, Wl 53706;

Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305;

Department of Biology, Syracuse University, Syracuse, NY 13244;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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1. Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif [J] . Castro DS, Skowronska-Krawczyk D, Armant O, Developmental cell . 2006,第6期

机译：proneural bHLH和Brn蛋白通过协同结合保守的DNA基序来整合神经源性程序
2. A calcium-initiated signaling pathway propagated through calcineurin and cAMP response element-binding protein activates proenkephalin gene transcription after depolarization. [J] . Hahm SH, Chen Y, Vinson C, Molecular pharmacology. . 2003,第6期

机译：通过钙调神经磷酸酶和cAMP反应元件结合蛋白传播的钙起始信号通路在去极化后激活前脑啡肽基因转录。
3. FoxA Proteins Regulate H19 Endoderm Enhancer E1 and Exhibit Developmental Changes in Enhancer Binding In Vivo [J] . Lingyun Long, Brett T. Spear Molecular and Cellular Biology . 2004,第21期

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4. Utilizing bioinformatics approaches for identifying binding sites in the drosophild genome for a developmentally important transcription factor protein [C] . Patel, H.B., Lee, . 2002

机译：利用生物信息学方法鉴定果蝇基因组中发展重要的转录因子蛋白的结合位点
5. Enhancer Binding Proteins Initiate and Propagate Multicellular Development in Myxococcus xanthus [D] . Giglio, Krista Michelle 2011

机译：增强剂结合蛋白启动并促进多发性粘液球菌的多细胞发育。
6. PNAS Plus: A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program [O] . Krista M. Giglio, Nora Caberoy, Garret Suen, 2011

机译：PNAS Plus：一连串的增强剂结合蛋白启动并传播了多细胞发育程序
7. A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program [O] . Giglio, Krista M., Caberoy, Nora, Suen, Garret, 2011

机译：一连串的增强调节剂结合蛋白启动并传播了多细胞发育程序
8. Phosphorylation of Intracellular IGF Binding Protein-3 by the IGF Signaling Cascade is Essential for Its Growth-Enhancing in Mammary Epithelial [R] . Cohick, W. S. 2004

机译：IGF信号级联对细胞内IGF结合蛋白-3的磷酸化对其在乳腺上皮细胞中的生长增强至关重要

A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program

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