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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Resolving the role of prenatal sex steroids in the development of digit ratio
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Resolving the role of prenatal sex steroids in the development of digit ratio

机译：解决产前性类固醇在数字比例发展中的作用

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摘要

Prenatal sex steroids [i.e., prenatal testosterone (PT), prenatal estrogen (PE)] are often implicated in the etiology of behaviors and diseases. They show sex differences (higher concentrations of PT to PE in males), with PT peaking at the end of the first trimester, and cause permanent "organizational" changes in the brain and other organ systems. It has been suggested that relative levels of PT and PE may have differential effects on fertility, speed, strength, aggression, autism, many cancers, and heart disease. However, PT and PE are difficult to assess, and this has prevented the establishment of convincing links. The relative lengths of the second and fourth digits [digit ratio (2D:4D)] is thought to correlate negatively with PT and positively with PE, thus affording us the possibility of establishing such links.
机译：产前性类固醇[即产前睾丸激素（PT），产前雌激素（PE）]通常与行为和疾病的病因有关。它们显示出性别差异（男性中PT对PE的浓度较高），并且在孕早期末期PT达到峰值，并引起大脑和其他器官系统的永久性“组织性”改变。已经提出，PT和PE的相对水平可能对生育力，速度，力量，攻击性，自闭症，许多癌症和心脏病有不同的影响。但是，PT和PE难以评估，这阻止了令人信服的链接的建立。第二和第四位数字的相对长度[数字比例（2D：4D）]被认为与PT呈负相关，与PE呈正相关，因此为我们提供了建立此类链接的可能性。

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