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Process for prenatal determination of foetal abnormalities and process for prenatal sex determination

机译:胎儿异常的产前确定过程和产前性别确定过程

摘要

Process for prenatal determination of foetal abnormalities and especially of chromosome aberrations such as trisomy 21, trisomy 18 or trisomy 13 as well as gene aberrations such as drepanocytosis, thalassaemia, mucoviscidosis, and the like and process for prenatal sex determination. These non-invasive processes for prenatal determination of cellular foetal abnormalities are characterised in that at the time of a collection of a sample of maternal blood, a fraction enriched with foetal cells is extracted from the said sample by bringing the said sample into contact with antibodies specific for foetal cells, and in that the said foetal cells are then detected by any appropriate means.
机译:产前确定胎儿异常的方法,尤其是染色体畸变,例如21三体,18三体或13三体,以及基因畸变,例如脱细胞,地中海贫血,粘膜粘连等,以及产前性别确定的方法。这些用于细胞胎儿异常的产前确定的非侵入性方法的特征在于,在收集母血样品时,通过使所述样品与抗体接触,从所述样品中提取富含胎儿细胞的级分。对胎儿细胞具有特异性,并且然后通过任何合适的手段检测所述胎儿细胞。

著录项

  • 公开/公告号FR2685777A1

    专利类型

  • 公开/公告日1993-07-02

    原文格式PDF

  • 申请/专利权人 BERTIN ET CIE;

    申请/专利号FR19910016407

  • 发明设计人 HACHE JEAN;EYDOUX PATRICE;

    申请日1991-12-31

  • 分类号C12Q1/68;C12Q1/6804;C12Q1/6841;G01N33/569;G01N33/68;

  • 国家 FR

  • 入库时间 2022-08-22 05:00:03

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