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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Solutes determine the temperature windows for microbial survival and growth
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Solutes determine the temperature windows for microbial survival and growth

机译:溶质确定微生物存活和生长的温度窗口

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摘要

Microbial cells, and ultimately the Earth's biosphere, function within a narrow range of physicochemical conditions. For the majority of ecosystems, productivity is cold-limited, and it is microbes that represent the failure point. This study was carried out to determine if naturally occurring solutes can extend the temperature windows for activity of microorganisms. We found that substances known to disorder cellular macromolecules (chaotropes) did expand microbial growth windows, fungi preferentially accumulated chaotropic metabolites at low temperature, and chemical activities of solutes determined microbial survival at extremes of temperature as well as pressure. This information can enhance the precision of models used to predict if extraterrestrial and other hostile environments are able to support life; furthermore, chaotropes may be used to extend the growth windows for key microbes, such as saprotrophs, in cold ecosystems and manmade biomes.
机译:微生物细胞,最终是地球的生物圈,在狭窄的物理化学条件下起作用。对于大多数生态系统而言,生产力受到寒冷的限制,而微生物代表了故障点。进行这项研究是为了确定天然存在的溶质是否可以延长微生物活动的温度范围。我们发现,使细胞大分子紊乱(离液序列高)的物质确实扩大了微生物的生长窗口,真菌在低温下优先积累了离液序列高的代谢产物,而溶质的化学活性决定了在极端温度和压力下微生物的存活率。这些信息可以提高用于预测地外和其他敌对环境是否能够维持生命的模型的精度;此外,在寒冷的生态系统和人造生物群落中,离液剂可用于扩展关键微生物如腐生菌的生长窗口。

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