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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Ancient mitochondrial M haplogroups identified in the Southwest Pacific
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Ancient mitochondrial M haplogroups identified in the Southwest Pacific

机译:在西南太平洋发现的古代线粒体单倍体

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摘要

Based on whole mtDNA sequencing of 14 samples from Northern Island Melanesia, we characterize three formerly unresolved branches of macrohaplogroup M that we call haplogroups M27, M28, and M29. Our 1,399 mtDNA control region sequences and a literature search indicate these haplogroups have extremely limited geographical distributions. Their coding region variation suggests diversification times older than the estimated date for the initial settlement of Northern Island Melanesia. This finding indicates that they were among the earliest mtDNA variants to appear in these islands or in the ancient continent of Sahul. These haplogroups from Northern Island Melanesia extend the existing schema for macrohaplogroup M, with many independent branches distributed across Asia, East Africa, Australia, and Near Oceania.
机译:基于来自北岛美拉尼西亚的14个样品的完整mtDNA测序,我们表征了宏观单体组M的三个以前未解析的分支,我们将其称为单体组M27,M28和M29。我们的1,399 mtDNA控制区序列和文献搜索表明,这些单倍群的地理分布极为有限。它们的编码区变化表明,多样化时间要比北岛美拉尼西亚最初定居的估计日期要早。这一发现表明,它们是最早出现在这些岛屿或萨胡尔古大陆的mtDNA变体之一。来自北岛美拉尼西亚的这些单倍群扩展了大单倍群M的现有模式,在亚洲,东非,澳大利亚和近大洋洲分布了许多独立的分支。

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