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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Polyketide and non-ribosomal peptide synthases: Falling together by coming apart
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Polyketide and non-ribosomal peptide synthases: Falling together by coming apart

机译：聚酮化合物和非核糖体肽合酶：通过分解而聚在一起

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摘要

Microorganisms have invented many devious ways to thwart their foes and survive in adverse environments. Non-motile microbes, especially ones that inhabit soil and marine environments, are noted for an ability to produce a wide range of chemicals (1). These are usually called "secondary metabolites," because of their seeming dispensability for the organism's ontogeny. It is obvious from the complex structures of such metabolites that their production involves unusual biochemistry as well as complex genetics devoted to the property of self-defense, intercellular communication, and other aspects of microbial life.
机译：微生物发明了许多巧妙的方法来挫败敌人并在不利的环境中生存。非运动微生物，特别是居住在土壤和海洋环境中的微生物，具有产生多种化学品的能力（1）。这些通常被称为“次级代谢产物”，因为它们似乎对生物体的个体发育具有可分配性。从此类代谢物的复杂结构中可以明显看出，它们的产生涉及异常的生物化学以及致力于自卫，细胞间通讯和微生物生活其他方面的复杂遗传学。

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