Structural analysis of the RSC chromatin-remodeling complex

Francisco J. Asturias; Wen-Hsiang Chung; Roger D. Kornberg; Yahli Lorch

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Structural analysis of the RSC chromatin-remodeling complex

机译：RSC染色质重塑复合物的结构分析

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Electron microscopy of the RSC chromatin-remodeling complex reveals a ring of protein densities around a central cavity. The size and shape of the cavity correspond closely to those of a nucleo-some. Results of nuclease protection analysis are consistent with nucleosome binding in the cavity. Such binding could explain the ability of RSC to expose nucleosomal DNA in the presence of ATP without loss of associated histones.

机译：RSC染色质重塑复合物的电子显微镜检查揭示了中央腔周围的蛋白质密度环。腔的大小和形状与核小体的大小和形状紧密对应。核酸酶保护分析的结果与腔中核小体结合一致。这种结合可以解释RSC在ATP存在下暴露核小体DNA的能力而不会丢失相关的组蛋白。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2002年第21期|p.13477-13480|共4页
作者
Francisco J. Asturias; Wen-Hsiang Chung; Roger D. Kornberg; Yahli Lorch;
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作者单位

Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Functional differences between RSC1 and RSC2, components of a for growth essential chromatin-remodeling complex of Saccharomyces cerevisiae, during the sporulation process [J] . Yukawa M, Koyama H, Miyahara K, FEMS Yeast Research . 2002,第2期

机译：RSC1和RSC2之间的功能差异是孢子形成过程中酿酒酵母生长必不可少的染色质重塑复合体的成分
2. The Genome-Wide Localization of Rsc9, a Component of the RSC Chromatin-Remodeling Complex, Changes in Response to Stress [J] . Marc Damelin, Itamar Simon, Terence I. Moy, Molecular cell . 2002,第3期

机译：Rsc9，RSC染色质重塑复合体的一个组成部分的全基因组本地化，对压力响应的变化
3. Members of the RSC Chromatin-Remodeling Complex Are Required for Maintaining Proper Nuclear Envelope Structure and Pore Complex Localization [J] . Laura C. Titus, T. Renee Dawson, Deborah J. Rexer, Molecular biology of the cell . 2010,第6期

机译：RSC染色质重塑复合体的成员对于维持适当的核包膜结构和孔复合体局部化是必需的
4. VLSI circuit complexity and decoding performance analysis for low-power RSC turbo-code and iterative block decoders design [C] . Hong, S., Stark, . 1998

机译：低功耗RSC Turbo码和迭代块解码器设计的VLSI电路复杂度和解码性能分析
5. Structural Insights into the Assembly and Dynamics of the ATPDependent Chromatin-Remodeling Complex SWR1. [D] . Nguyen, Vu Quang. 2014

机译：对ATP依赖的染色质重塑复合体SWR1的组装和动力学的结构见解。
6. Structural analysis of the RSC chromatin-remodeling complex [O] . Francisco J. Asturias, Wen-Hsiang Chung, Roger D. Kornberg, 2002

机译：RSC染色质重塑复合物的结构分析
7. Structural analysis of the RSC chromatin-remodeling complex [O] . Asturias, Francisco J., Chung, Wen-Hsiang, Kornberg, Roger D., 2002

机译：RSC染色质重塑复合物的结构分析

Structural analysis of the RSC chromatin-remodeling complex

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