Anti-cancer agent-induced dyspnea

Maraveyas Anthony; Johnson Miriam

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Anti-cancer agent-induced dyspnea

机译：抗癌药引起的呼吸困难

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Anti-cancer agents can cause dyspnea through a variety of mechanisms; cardiac toxicity, pulmonary toxicity, and vascular thrombotic events. Toxicity of the anthracyclines and other traditional chemotherapy drugs are well known, but problems associated with the newer biological agents are less well recognized. As palliative chemical therapies are being given to cancer patients even in advanced disease, it is important that palliative care professionals are aware of potential adverse effects that range from deteriorating dyspnea to rapid death. This article summarizes the agents associated with such toxicity, the mechanisms underpinning the effect on dyspnea, and the varying clinical presentations and management.

机译：抗癌药可通过多种机制引起呼吸困难。心脏毒性，肺毒性和血管血栓形成事件。蒽环类药物和其他传统化学疗法药物的毒性是众所周知的，但是与新型生物制剂有关的问题却鲜为人知。由于即使在晚期患者中也可以对癌症患者进行姑息化学疗法，姑息治疗专业人员必须意识到潜在的不良反应，从恶化的呼吸困难到迅速死亡，这一点很重要。本文总结了与此类毒性有关的药物，对呼吸困难的作用基础的机制以及各种临床表现和治疗方法。

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来源
《Progress in Palliative Care》 |2011年第5期|p.235-242|共8页
作者
Maraveyas Anthony; Johnson Miriam;
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作者单位

Queen's Centre for Haematology & Oncology, Hull and York Medical School, University of Hull, Hull, UK 2: Hull and York Medical School, University of Hull, St Catherine's Hospice, North Yorkshire YO12 5RE, UK;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
原文格式 PDF
正文语种 eng
中图分类
关键词
Chemotherapy; Anti-cancer agent; Dyspnea;

机译：化学疗法抗癌剂;呼吸困难;

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Anti-cancer agent-induced dyspnea

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