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Everyday Exposures and Breast Cancer

机译:日常接触和乳腺癌

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摘要

Thank you for focusing this year on environmental factors in cancer, a key arena for efforts to significantly change the cancer burden in this country through primary prevention of disease. I am pleased to have the opportunity to contribute to this dialogue. My remarks are grounded in my research about environmental factors and breast cancer and have particular relevance for other hormonal cancers as well-for example, prostate, testicular, ovarian, and endometrial cancers. I begin with a thought experiment about the process of discovery in cancer etiology. This perspective underlies my recommendations for fundamental change in the evidence we use to find and attack the environmental causes of a disease like breast cancer. Then I will address what we know now about three biological mechanisms that may link environmental pollutants and breast cancer and about human exposures to suspect chemicals. Finally, I discuss the critical next steps to act on and expand our knowledge.
机译:感谢您今年将重点放在癌症的环境因素上,这是通过基本疾病预防来显着改变该国癌症负担的主要领域。我很高兴有机会为这次对话做出贡献。我的言论基于我对环境因素和乳腺癌的研究,并且与其他激素癌(例如前列腺癌,睾丸癌,卵巢癌和子宫内膜癌)特别相关。我从关于癌症病因发现过程的思想实验开始。这种观点为我提出了根本性改变的建议提供了基础,我们将用这些证据来发现和应对诸如乳腺癌之类的疾病的环境原因。然后,我将介绍我们现在所知的关于可能将环境污染物与乳腺癌联系起来的三种生物学机制以及关于人类接触可疑化学物质的知识。最后,我讨论了关键的后续步骤,以采取行动并扩展我们的知识。

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  • 来源
    《Reviews on environmental health》 |2010年第1期|p.1-7|共7页
  • 作者

    Julia G. Brody;

  • 作者单位

    Silent Spring Institute, 29 Crafts Street, Newton, Massachusetts 02458, USA;

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  • 原文格式 PDF
  • 正文语种 eng
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