Action at a Distance, Circa Early 1950s

DIANA KWON

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Action at a Distance, Circa Early 1950s

机译：在20世纪50年代初期，大约一段距离

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What do nerves need in order to grow? That question first caught Rita Levi-Montalcini's attention in the 1930s, when she came across a recent paper by embryologist Viktor Hamburger. After observing that clipping the wing bud off chicken embryos stunted the growth of spinal nerves and ganglia on the side of the body with the excision, Hamburger reported that signals from the limb drove the growth and differentiation of immature cells in the central nervous system. Levi-Montalcini was intrigued. But after repeating the embryo experiments and finding that the chick's nerve cells continued to develop after amputation and died later-just before reaching their target tissue-she came to a different conclusion. Rather than failing to initiate nerve growth, she hypothesized, the animals were unable to sustain the growing cells, causing a degenerative process that limited their proliferation.

机译：神经需要什么来成长？当她遇到胚胎viktor汉堡包时，这是第一次抓到了20世纪30年代的rita levi-montalcini的注意力。观察夹芽后鸡胚后，脊髓神经和神经节的生长随着切除，汉堡报道，来自肢体的信号推动了中枢神经系统中未成熟细胞的生长和分化。 Levi-Montalcini感兴趣。但在重复胚胎实验并发现小鸡的神经细胞在截肢后继续发展，并在达到目标组织之前继续发生 - 她得出了不同的结论。她假设的而不是未能发起神经生长，而是无法维持生长细胞，导致改变过程限制其增殖。

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《The Scientist》 |2020年第12期|60-60|共1页
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DIANA KWON;
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Action at a Distance, Circa Early 1950s

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