In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription.

C H Clayman; M S Collett; A J Faras

首页> 外文期刊>Journal of Virology >In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription.

【24h】

In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription.

机译：通过RNA定向的DNA聚合酶对禽类血管基因组的体外转录：放线霉素D对转录程度的影响。

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The minus-strand component of double-stranded DNA synthesized by the avian oncornavirus RNA-directed DNA polymerase in vitro represents as much of the nucleotide sequences of the viral genome as single-stranded DNA synthesized in the presence of actinomycin D. Since actinomycin D inhibits doublestranded DNA formation, we propose that the principal effect of the drug on RNA-directed DNA synthesis is the reduction in synthesis of plus-strand DNA, thereby allowing single-stranded minus-strand DNA to accumulate. This effect, rather than increasing the extent of genome transcription, is responsible for the more uniform nature of the DNA transcripts synthesized in the presence of actinomycin D.

机译：在体外，由禽类上的双链DNA的双链DNA的减去分量代表了病毒基因组的大部分核苷酸序列，因为在放线霉素D存在下合成的单链DNA。由于放线霉素D抑制双层DNA形成，我们提出了药物对RNA定向的DNA合成的主要作用是加股DNA的合成还原，从而允许单链的负链DNA积聚。这种效果，而不是提高基因组转录的程度，负责在放线蛋白D存在下合成的DNA转录物的更均匀性。

著录项

来源
《Journal of Virology》 |1977年第1期|共4页
作者
C H Clayman; M S Collett; A J Faras;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);
原文格式 PDF
正文语种
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription. [J] . C H Clayman, M S Collett, A J Faras Journal of Virology . 1977,第1期

机译：通过RNA定向的DNA聚合酶对禽类血管基因组的体外转录：放线霉素D对转录程度的影响。
2. In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription. [J] . C H Clayman, M S Collett, A J Faras Journal of Virology . 1977,第1期

机译：通过RNA定向的DNA聚合酶对禽类血管基因组的体外转录：放线霉素D对转录程度的影响。
3. In vitro transcription of theavian oncornavirus genome by the RNA-directed DNA polymerase: analysis of DNA transcripts synthesized in reconstructed enzymatic reactions. [J] . M S Collett, A J Faras Journal of Virology . 1977,第1期

机译：通过RNA定向的DNA聚合酶在体外转录Theavian Oncornavirus基因组：在重建的酶促反应中合成的DNA转录物分析。
4. Modelling the Polymerase Chain Reaction for DNA Amplification ofBacterial Genomes [C] . Triinu Koressaar, Maido Remm Annual Meeting of the Cambridge Healthtech Institute . 2006

机译：对聚合酶链反应进行建模，用于对细菌基因组的DNA扩增
5. The Origin and Evolution of Plant-Specific RNA Polymerases and Genes Involved in RNA-Directed DNA Methylation [D] . Trujillo, Joshua Tyler. 2019

机译：植物特异性RNA聚合酶的起源和演变和参与RNA定向的DNA甲基化的基因
6. In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription. [O] . C H Clayman, M S Collett, A J Faras 1977

机译：RNA定向的DNA聚合酶体外转录禽流感病毒基因组：放线菌素D对转录程度的影响。
7. In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription [O] . C H Clayman, M S Collett, A J Faras 1977

机译：通过RNA定向的DNA聚合酶在禽类oncornavirus基因组的体外转录：放线菌素D对转录程度的影响

In vitro transcription of the avian oncornavirus genome by the RNA-directed DNA polymerase: effect of actinomycin D on the extent of transcription.

摘要

著录项

相似文献

相关主题

期刊订阅