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脑血管病电子杂志(英文)

脑血管病电子杂志(英文)

  • 发文量：13
  • 被引量：0
  • H指数：0
  • 开始收录时间：2018,1(1)
  • CNKI综合因子：0.0
  • 维普期刊影响因子： -
  • 万方期刊影响因子：0.0
  • 创刊时间：2018
  • 国内刊号/CN：11-9366/R
    国际刊号/ISSN：2096-1111
  • 发行周期：季刊
    邮发代号：
  • 主管单位：国家卫生和计划生育委员会
    主办单位：中华医学电子音像出版社
脑血管病电子杂志(英文)-联系信息
  • 主编：Shu-Sen Zheng
  • 电话：0571-87236467
  • 邮箱：jcvdcn@hotmail.com;jcvdcn@163.com
  • 地址：79 Qingchun Road,huangzhou
  • 邮编：310003
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脑血管病电子杂志(英文) >2020年第3期

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  • 摘要：Background: DNA banking is increasingly applied to collect genetic materials for biomedical studies. Traditionally, the source of DNA banking is from the anti-coagulated blood samples as it is easy to isolate cells from the samples for DNA extraction. However, substantial portion of clinical blood samples is coagulated. Because of the difficulty to release blood cells from the clots for DNA extraction, coagulated blood samples are not used for DNA banking. Methods: In this study, we developed a simple procedure for high-throughput DNA extraction from coagulated blood samples for DNA banking. Results: We showed that the extracted DNA is the same as the one extracted from anti-coagulated blood samples as reflected by the size distribution and genetic variants across all coding genes. Conclusions: We developed a simply procedure for high-throughput DNA extraction from coagulated blood cells. Validation results show that the DNA from coagulated blood cells is the same as the DNA from the anti-coagulated blood cells.
  • 摘要：Background:A rapid elevation of post-ischemic circulating hepatocyte growth factor(HGF)levels has been reported in acute vascular disease including stroke.However,the impact of transient ischemic attack(TIA)on circulating HGF has never been studied.Methods:Patients with an onset of either stroke or TIA within the past 30 days were enrolled.Based on the ischemic event,the patients were divided into a stroke group and a TIA group.Blood samples were collected at enrollment and at follow-up visits at one,three,and six months until a recurrent cerebral ischemic event.Plasma levels of HGF were measured using an enzyme-linked immunosorbent assay and logarithmically transformed to eliminate skewness.Results:Thirty-six patients were enrolled in the study,with 20 in the stroke group and 16 in the TIA group.The dynamic HGF levels post-ischemia showed distinct patterns between the two groups.A significant decrease of HGF levels was observed in the stroke group,from 2.62±0.18 ng/mL within 30 days after stroke to 2.41±0.22 ng/mL beyond 30 days(P=0.026);however,no significant change was found in the TIA group(2.22±0.17 ng/mL vs.2.19±0.16 ng/mL,P=0.990).A multivariate regression analysis showed a last event of stroke and a comorbidity of systemic atherosclerotic disease(SAD)were independently associated with higher levels of HGF.Subgroup analyses showed HGF levels decreased from 2.64±0.22 ng/mL within 30 days after stroke to 2.36±0.18 ng/mL beyond 30 days in patients without SAD(P=0.008),but not in patients with SAD(P=0.700).Conclusion:Our data indicate that in patients without SAD,circulating HGF is a potential biomarker to distinguish between stroke and TIA.
  • 摘要：The Sonic microcatheter,a new type of dimethylsulfoxide-compatible detachable tip microcatheter,is as safe and effective as the Marathon microcatheter.This review summarized the clinical use of the Sonic microcatheter,including cerebral arteriovenous malformations,dural arteriovenous fistulas,cerebral aneurysms,and vascular malformations of the spinal cord.The Sonic microcatheter promotes the emergence of the“pressure cooker technique”as well as new techniques for intravenous embolization of cerebral arteriovenous malformations.
  • 摘要：Scope Journal of Cerebrovascular Disease welcomes original research articles,review articles,editorials,and others in the field of medicine,especially the cerebrovascular disease,from any part of the world.Editorial process Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,and then either accepted for publication or rejected by the chief editor.
  • 摘要：Objective:To explore the clinical efficacy of neuroendoscopy combined with lateral ventricle drainage and urokinase infusion for the treatment of hypertensive intraventricular hemorrhage.Methods:A retrospective analysis of 20 patients diagnosed with intraventricular hemorrhage between March 2017 and August 2018 at the First Affiliated Hospital of Medical College,Shihezi University(Shiohezi,China)was performed.While actively treating primary lesions,20 patients with intraventricular hemorrhage were selected and treated using minimally invasive neuroendoscopic removal of intraventricular hematoma combined with lateral ventricular drainage and urokinase perfusion according to each patient’s condition.Results:One day after surgery,head computed tomography examination revealed that>50% of the hematoma in the lateral ventricle was removed in 14 cases,and 20%-50% of the hematoma in the other 6 cases.After follow-up,13 patients exhibited satisfactory recovery,5 died(3 due to lung infection,1 due to intracranial infection,and 1 due to multiple organ failure),and 2 were in a vegetative state.Conclusion:Neuroendoscopy should be used as much as possible in treating intraventricular hemorrhage given its advantages of minimal injury,complete removal of hematoma,high safety,and wide clinical applicability.
  • 摘要：Scope Journal of Cerebrovascular Disease welcomes original research articles,review articles,editorials,and others in the field of medicine,especially the cerebrovascular disease,from any part of the world.Editorial process Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,and then either accepted for publication or rejected by the chief editor.Most of submissions accepted for publication may undergo revisions recommended by the reviewers,editors,or statistical advisers.
  • 摘要：Background:Endovascular coiling for wide-neck aneurysms with a branch arising from the aneurysmal sac is challenging and sometimes considered impossible.This study aims to present our experience in treating wide-neck internal carotid artery(ICA)aneurysms with a posterior communicating artery(PComA)arising from the sac using a strategy of stenting the ICA and intentional compartmentalization to preserve the flow in the PComA.Methods:Eight consecutive cases of wide-neck ICA aneurysms with a fetal-type PComA arising from the aneurysmal sac were embolized from January 2015 to June 2018 at the First Affiliated Hospital,College of Medicine,Zhejiang University.Demographics,angiographic technique,procedural complications and clinical outcomes were reviewed.Results:There were 2 men and 6 women ranging from 56 to 81 years of age.Of the 8 cases,3 were ruptured and 5 were unruptured aneurysms.Stents were successfully deployed in all 8 cases.Near-complete occlusion was achieved in 3 cases(37.5%),neck remnant in 4(50%)and sac remnant in one(12.5%)of the cases.One case suffered transient ischemic attack after procedure completion.The clinical outcome was favorable in all 8 cases(modified Rankin scale 0-1).No rebleeding occurred during clinical follow-up.Conclusion:Stent-assisted compartmentalized embolization is feasible and safe in the treatment of wide-neck ICA aneurysm with a PComA arising from the sac.
  • 摘要：Chronic internal carotid artery occlusion(CICAO)is a chronic cerebrovascular disease which,from various causes,leads to progressive stenosis of the internal carotid artery lumen and finally to complete occlusion.With an aging society,the detection rate of CICAO is increasing year by year,with the highest incidence of CICAO in elderly men.The main clinical manifestations of CICAO are ischemic stroke and transient ischemic attack.Drug therapy is the first choice for asymptomatic CICAO,and surgical treatment is an optional means of improving prognosis for symptomatic CICAO that cannot be controlled by drugs.The selection of indications needs further study.This article reviews the latest research progress in the epidemiology,etiology,clinical features,imaging analysis,and treatment of CICAO in order to guide clinical diagnosis and treatment.
  • 摘要：Scope Journal of Cerebrovascular Disease welcomes original research articles,review articles,editorials,and others in the field of medicine,especially the cerebrovascular disease,from any part of the world.Editorial process Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,and then either accepted for publication or rejected by the chief editor.
  • 摘要：Background: Many authors have overlooked the intracranial distribution of the accessory meningeal artery (AMA). Blindness after AMA onyx embolization led us to the conclusion that the intracranial branches of the AMA should be emphasized. Methods: Previous literatures regarding the anatomy of the AMA were reviewed,with emphasis on its intracranial branches. Expected Outcomes: On the basis of the previous description,approximately 10% of the blood flow in the AMA reaches the intracranial territory and 90% is carried to the extracranial structures. Although the intracranial part of the AMA is small,it distributes to the semilunar ganglion nerve and anastomoses with the ophthalmic artery. Its function and importance should not be overlooked and should play an important role in cerebrovascular intervention.
  • 摘要：Background: Ischemic stroke accounts for approximately 80% of all cases of stroke and has the highest rates of morbidity,disability,mortality,and recurrence. The neutrophil-to-lymphocyte ratio (NLR) is a novel,feasible marker representing an integrated response to inflammation. The purpose of the current review is to evaluate all available evidence from clinical observational trials about the relationships between NLR and ischemic stroke. Methods: We searched PubMed,Embase,and CNKI for clinical observational trials on NLR published up to August 1,2018,and made a brief summary about the predictive value of the correlation between NLR and ischemic stroke. Results: A high NLR is associated with increased risk of developing stroke and is a new addition to the traditional risk factors of atrial fibrillation and carotid artery stenosis. NLR on admission is an independent predictor of short- and long-term mortality in patients with acute ischemic stroke. In patients receiving recombinant tissue plasminogen activator or endovascular treatments,high NLR was reported with higher mortality or major disability. Conclusion: NLR provides an easy,useful method to predict the incidence,severity,and prognosis of ischemic stroke;thus,it can emerge as a new potential target for anti-inflammatory treatment and development of therapeutic strategies.
  • 摘要：Background: With the aging society in China and the increasing incidence of cardiovascular and cerebrovascular diseases,spontaneous cerebral hemorrhage with the use of oral clopidogrel has become common in patients. Owing to its inhibition of platelet aggregation,oral clopidogrel results in a high incidence of postoperative intracranial rebleeding,and the prognosis is poor. The purpose of this study is to determine the effect of perioperative management of spontaneous intracerebral hemorrhage (SICH) using oral clopidogrel on postoperative rebleeding. Methods: From January 2010 to June 2018,64 patients with SICH who took clopidogrel orally and finally received surgical treatment were selected from Huzhou First People’s Hospital and the Second Affiliated Hospital of Wenzhou Medical University. The influencing factors of postoperative rebleeding were analyzed via a case-control study. Results: All patients with SICH were divided into two groups according to the standard time of drug withdrawal before surgery: drug withdrawal at < 3 days and ≥ 3 days. The incidence of postoperative rebleeding after drug withdrawal at ≥ 3 days was significantly lower than that after drug withdrawal at < 3 days. Thereafter,all patients were divided into two groups according to the adenosine diphosphate (ADP) inhibition rate detected using a thromboelastography monitor: ADP inhibition rate of < 60% and ≥ 60%. The incidence of postoperative rebleeding in the ADP inhibition rate of < 60% group was significantly lower than that in the ADP inhibition rate of ≥ 60% group. In addition,drug withdrawal at ≥ 3 days and ADP inhibition rate of < 60% had a synergistic effect on the prevention of postoperative rebleeding. Conclusions: Patients with drug withdrawal at ≥ 3 days can undergo active early surgery. The ADP inhibition rate of ≥ 60% can be used as the predictive index of high-risk postoperative rebleeding in patients with SICH taking oral clopidogrel. By reducing the ADP inhibition rate to < 60%,the incidence of postoperative rebleeding can also be reduced.
  • 摘要：Background: Copeptin is a biomarker for brain injury. However,it is unclear whether it is discriminative regarding in-hospital major adverse events (IMAEs),including acute lung injury,acute traumatic coagulopathy,progressive hemorrhagic injury and post-traumatic cerebral infarction,in patients with traumatic brain injury (TBI). This study was aimed at investigating the relationship between the serum copeptin level and occurrences of IMAEs. Methods: In this multicenter observational study,we recruited 173 severe TBI patients and 173 healthy controls. Serum levels of copeptin,interleukin-6,tumor necrosis factor-alpha,C-reactive protein,myelin basic protein,glial fibrillary astrocyte protein,S100B,neuron-specific enolase,phosphorylated axonal neurofilament subunit H,tau protein and ubiquitin carboxyl-terminal hydrolase L1 were quantified using available enzyme-linked immunosorbent assays. Areas under the receiver operating characteristic curves (AUCs) were estimated to determine and compare their discriminatory ability for IMAEs. Results: Patients had dramatically elevated levels of the afore-mentioned biomarkers,as compared with controls. In the discrimination of IMAEs,serum copeptin had a significantly higher AUC than serum interleukin-6,tumor necrosis factor-alpha and C-reactive protein and its AUC was similar to that of the Glasgow coma scale (GCS) score and the other remaining biomarkers mentioned above. Except copeptin,no other biomarkers could significantly improve the AUC of the GCS score. Conclusion: Serum copeptin levels combined with the GCS score might aid in discriminating IMAEs following TBI.
  • 摘要：Background: To improve the biological compatibility of pure polycaprolactone (PCL) nanofibrous scaffolds by co-spinning of hyaluronic acid (HA) and PCL,and to evaluate the value of HA-PCL scaffolds in nerve tissue engineering by observing the growth of neural stem cells (NSCs) on them. Methods: Using traditional electrospinning technology,HA and PCL were spun into three kinds of random,aligned,and extremely aligned scaffolds in a ratio of 1:5 and 1:10,and the pure PCL scaffold was prepared at the same time. The sequencing and fiber diameters of various nanofibrous scaffolds were determined by electron microscopy. Then,NSCs were inoculated on the 9 nanofibrous scaffolds,and their proliferation was determined by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide] assay after 5 days. Results: Scaffolds of pure PCL,1:5 HA-PCL,and 1:10 HA-PCL were successfully prepared,whose diameter was about 200 nm and which were divided into random,aligned,and extremely aligned scaffolds by electron microscopy. The MTT assay showed no significant difference in the proliferation of NSCs on 1:10 HA-PCL scaffolds and pure PCL scaffolds. The proliferation of NSCs on 1:5 HA-PCL scaffolds was better than that of 1:10 HA-PCL and pure PCL scaffolds. On the 1:5 HA-PCL scaffold,the more aligned the scaffold is,the faster cells proliferate. Conclusions: HA can effectively increase the tissue compatibility of PCL scaffolds and promote the proliferation of NSCs. The aligned nanofibrous scaffold is more beneficial to the proliferation of NSCs.
  • 摘要：Scope Journal of Cerebrovascular Disease welcomes original research articles,review articles,editorials and others in the field of medicine,especially the cerebrovascular disease,from any part of the world. Editorial process Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,and then either accepted for publication or rejected by the chief editor. Most of submissions accepted for publication may undergo revisions recommended by the reviewers,editors or statistical advisers. A decision takes from two weeks to three months. Publication varies from two to six months after final acceptance. Proofs of edited articles and illustrations are sent to the corresponding author for correction and reply to any queries from editors. A sample copy of the journal containing the articles will be forwarded to the corresponding author within a few days of publication.
  • 摘要：Based on the mobile Internet, Internet of Things, big data, cloud computing,“intelligentization” and other technologies, a safe and reliable management platform for integrating information about acute ischemic stroke (AIS) thrombolysis with unified standards should be established. The management platform should include intelligent screening of high-risk groups and servers for monitoring them, server analysis of patient medical records, a server for supervision and integrated management of patient education, an integrated system of healthcare records, and a clinical decision-support system for AIS emergencies. Such a system would constitute a standardized data capture and integrated intelligent analysis system for the key information necessary in thrombolytics. In this way a human-oriented prevention and intervention mechanism for continuous care and prevention of stroke would be formed to achieve the collection and intelligent analysis of key information in drug thrombolysis. It would provide data support for AIS thrombolytics management strategies that would improve the coverage of drug thrombolysis in primary hospitals, and also optimize AIS emergency processes to increase the success rate of thrombolysis.
  • 摘要：Objective: To summarize a decade of research on various aspects of Sowthistle-leaf Ixeris seedling for acute cerebral infarction. Methods: Thirty-six papers were collected from searches of CNKI, Wanfang, PubMed, and other databases and then they were summarized. Results: Researchers have carried out widespread and various pharmacological studies of Sowthistle-leaf Ixeris seedling, and have pursued different research directions on its etiology and pathogenesis, syndrome differentiation and treatment methods for acute cerebral infarction (ischemic stroke). With the development of Chinese medicine, its safety and non-toxic side effects have been recognized by the majority of scholars. The research results have contributed significantly to the treatment of acute cerebral infarction by Sowthistle-leaf Ixeris seedling. Conclusion: Sowthistle-leaf Ixeris seedling has extensive medicinal value and unique advantages in the treatment of acute cerebral infarction, especially in expanding brain vessels, increasing blood flow, reducing thrombosis, protecting brain cells, improving neurological impairment, and it has no toxic side effects.
  • 摘要：Background: DNA banking is increasingly applied to collect genetic materials for biomedical studies. Traditionally, the source of DNA banking is from the anti-coagulated blood samples as it is easy to isolate cells from the samples for DNA extraction. However, substantial portion of clinical blood samples is coagulated. Because of the difficulty to release blood cells from the clots for DNA extraction, coagulated blood samples are not used for DNA banking. Methods: In this study, we developed a simple procedure for high-throughput DNA extraction from coagulated blood samples for DNA banking. Results: We showed that the extracted DNA is the same as the one extracted from anti-coagulated blood samples as reflected by the size distribution and genetic variants across all coding genes. Conclusions: We developed a simply procedure for high-throughput DNA extraction from coagulated blood cells. Validation results show that the DNA from coagulated blood cells is the same as the DNA from the anti-coagulated blood cells.
  • 摘要：Background: Through endovascular therapy of brain arteriovenous malformations (AVMs), the curative effect of embolization and the post-embolic complications are still being debated. This study aims to assess the outcomes, complications and angiographic predictors of curative effects after an initial Onyx-18 embolization for supratentorial brain AVMs (sbAVMs). Methods: The clinical and angiographic characteristics of sbAVM patients presenting with initial embolization at our institutions from 2005 to 2008 were retrospectively reviewed. Univariate and multivariate analyses were conducted to assess the angiographic features in patients with and without total occlusion of sbAVMs. Results: In 130 patients with sbAVMs who were initially embolized by Onyx-18, there were 28 complete (21.5%), and 102 non-complete embolizations (78.5%). Non-technical peri-procedural hemorrhage occurred in 5 cases, transient neurological deficit in 13 cases, persistent neurological deficit in 9 cases, and death in one case. There was no significant difference in complications between patients with and without complete embolization. By univariate analyses, small size (≤ 3 cm), single feeding artery, double feeding artery, terminal feeders, single drainage vein, and superficial venous drainage were associated with cure by embolization (P < 0.05). Single drainage vein (P = 0.003) and 1–2 feeding arteries (P = 0.009) were correlated with AVM volume reduction in the multivariate model. Conclusions: Initial Onyx-18 embolization for sbAVMs can achieve satisfactory outcomes. Curative embolization can be achieved in the initial single session with low morbidity, and it is not correlated with complications. A single draining vein and 1–2 arterial feeders could be predictive for curative embolization.
  • 摘要：Background: The goal of this paper is to summarize the pupillary changes after papaverine application in intracranial aneurysms surgeries. Methods: We retrospectively analyzed the clinical data of six intracranial aneurysm patients who were treated with papaverine application during surgery. Results: Two cases of ipsilateral papillary dilation, two cases of contralateral pupillary dilation, one case of bilateral pupillary dilation, and one case of asymmetric pupils were observed after craniotomy. All of these pupillary changes resolved in one-half to three hours without neurological deficits. Conclusions: Pupillary changes after the use of papaverine in intracranial aneurysm surgeries may be an instantaneous reaction to papaverine. Most cases can return to normal after close observation.
  • 摘要：CLINICAL DATA A 29-year-old Chinese male patient was admitted to our hospital in June 2016 with a diagnosis of traumatic internal carotid cavernous fistula and cranioplasty postoperative infection, suffering from right eye proptosis and scalp infection for one and one-half years. This patient sustained a traumatic brain injury after a motorcycle accident three years earlier, initially diagnosed as “bilateral frontal lobe contusion with hematoma and extensive anterior skull fracture” at a local hospital. Cranial hematoma removal and decompressive craniectomy were performed immediately, with a cranioplasty three months later. One and one-half years ago, a local hospital diagnosed, but did not treat, a carotid cavernous fistula based on a protrusion in the right eye and a pulsatile uplift in the upper part of the right eye socket. Over the past year, these symptoms gradually worsened, but the blurring of the right eye was similar to that after surgery.
  • 摘要：Scope Journal of Cerebrovascular Disease welcomes original research articles, review articles, editorials and others in the field of medicine, especially the cerebrovascular disease, from any part of the world.

    脑血管病电子杂志(英文)的期刊信息

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    • 创刊时间：2018
    • 地区：CN
    • 语言：中文
    • 热门主题：STROKE INTRACRANIAL INSTRUCTIONS ACUTE TRAUMATIC AUTHORS MENINGEAL MANAGEMENT MALFORMATIONS LYMPHOCYTE
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    • 邮编：310003
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