• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pharmacoepidemiology and drug safety >Determinants of non-compliance with lipid-lowering therapy in hyperlipidemic patients.
【24h】

Determinants of non-compliance with lipid-lowering therapy in hyperlipidemic patients.

机译：高脂血症患者不遵守降脂治疗的决定因素。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: In order to assess the determinants of non-compliance with a lipid-lowering therapy, a prospective study of the hyperlipidemic Korean subjects was carried out. METHODS: A total of 1019 patients was observed by 46 family physicians for the period of 1 year from January 1999 to January 2000. To ascertain the compliance associated with a lipid lowering drug (Simvastatin), we regularly followed up the hyperlipidemic patients at intervals of 4, 12 and 24 weeks. The criterion for evaluating compliance is to measure clinic attendance. Using a structured questionnaire, patients and physicians were asked about risk factors for the compliance. RESULTS: During the first 24 weeks of treatment, the lipid-lowering medication was continued by 52.3% and discontinued by 19.7%. The remaining 28% dropped out. Patient-related factors for non-compliance were young age, current smoker, lack of low fat diet and exercise, new user, no concomitant medication, and occurrence of adverse reactions. Physician-related factors for non-compliance were low patients' satisfaction with the physician, small number of hyperlipidemic patients per month and working in a relatively small hospital. CONCLUSIONS: Compliance with the lipid-lowering therapy was relatively low and several factors for non-compliance were detected.
机译：目的：为了评估不符合降脂治疗的决定因素，对高脂血症韩国人进行了前瞻性研究。方法：从1999年1月至2000年1月，在46年的家庭医生中共观察了1019例患者，为期1年。为确定与降脂药（Simvastatin）相关的依从性，我们定期对高脂血症患者进行随访，随访时间为4、12和24周。评估依从性的标准是衡量门诊人数。使用结构化调查表，询问患者和医生有关依从性的危险因素。结果：在治疗的前24周中，降脂药物持续52.3％，停药19.7％。其余的28％退学了。与患者不依从相关的因素包括年龄，吸烟者，缺乏低脂饮食和运动，新使用者，无伴随用药以及不良反应的发生。与医师不符的医师相关因素包括患者对医师的满意度低，每月高血脂患者人数少以及在相对较小的医院工作。结论：降脂治疗的依从性相对较低，并且发现了一些违规因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号