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A study of drug use during pregnancy in a teaching hospital in western Nepal.

机译:在尼泊尔西部的一家教学医院进行的妊娠期用药研究。

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Information on the use of drugs during pregnancy is scarce and rather anecdotal. Careful consideration of the benefit to the mother and the risk to the fetus is required when prescribing drugs during pregnancy. The aim of this study was to gain knowledge on this issue in western Nepal. 2156 prescriptions of pregnant women were collected at random from the antenatal care (ANC) in obstetrics out-patient department (OPD) at Manipal Teaching Hospital (MTH), Nepal and analyzed for this study. The mean maternal age and hemoglobin concentration were 25 years and 12.21 g/dl, respectively. Twenty-three percent women attended obstetric OPD due to maternal disorders other than routine ANC (77%). Problem oriented drug use was due to nausea/vomiting (4.7%), dyspepsia (3.1%), and per vaginal spotting/bleeding (3.4%), mainly. Most of the women got 2-3 drugs and commonly included nutritional supplementation and tetanus toxoid. The average number of drugs/prescription was 2.00, 15.37% and 64.8% drugs were prescribed bygeneric name and as fixed dose combinations, respectively. The most commonly prescribed drugs were nutritional supplements like iron, folate, calcium, vitamins (72.8%), followed by tetanus toxoid (12.4%), gastrointestinals (5%), antimicrobials (4.6%), etc. Though, the selection of drugs was rational in most of the cases, some anomalies were observed and discussed with the clinicians. Our data reflect the general extent and prescribing pattern for those Nepalese pregnant women attending hospital in western Nepal.
机译:怀孕期间使用毒品的信息很少,而且很少发生。在怀孕期间开药时,需要仔细考虑对母亲的益处和对胎儿的风险。这项研究的目的是在尼泊尔西部获得有关此问题的知识。从尼泊尔马尼帕尔教学医院(MTH)的产科门诊(OPD)的产前护理(ANC)中随机收集了2156份孕妇处方,并对其进行了分析。孕妇平均年龄和血红蛋白浓度分别为25岁和12.21 g / dl。有23%的妇女因非常规ANC的产妇疾病而参加了产科OPD(77%)。以问题为导向的药物使用主要是由于恶心/呕吐(4.7%),消化不良(3.1%)和每个阴道斑点/出血(3.4%)。大多数妇女服用2-3种药物,通常包括营养补充剂和破伤风类毒素。药品/处方的平均数量分别为2.00、15.37%和64.8%,分别由通用名称和固定剂量组合指定。最常用的处方药是营养补品,如铁,叶酸,钙,维生素(72.8%),其次是破伤风类毒素(12.4%),胃肠道(5%),抗菌剂(4.6%)等。尽管如此,药物的选择在大多数情况下是合理的,观察到一些异常并与临床医生讨论。我们的数据反映了尼泊尔西部尼泊尔住院的尼泊尔孕妇的总体病情和处方模式。

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