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首页> 外文期刊>Poultry Science >Circulating corticosterone reaction to restraint and adrenocorticotropin hormone administration in white leghorns selected for immune response traits.
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Circulating corticosterone reaction to restraint and adrenocorticotropin hormone administration in white leghorns selected for immune response traits.

机译：循环皮质激素反应对选择用于免疫应答性状的白色来亨鸡的约束和肾上腺皮质激素的激素给药。

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摘要

Corticosterone plasma concentration was measured in a random-bred control line and in 3 White Leghorn chicken lines previously selected over 9 generations for 3 different in vivo immune responses: high antibody response to Newcastle disease virus vaccine 3 wk after vaccination (ND3), high cell-mediated immune response (response to phytohemagglutinin, PHA), and high phagocytic activity measured as carbon clearance (CC). The objective of the study was to estimate if selection on immune response had an effect on the response to stress assessed by measures of corticosterone concentration before and after physical stress or adrenocorticotropin hormone injection and if the effect was dependent on the immune response trait that had been selected for, by joint analyses of immune responses and concentrations. The mean values of plasma corticosterone measures did not differ between lines, indicating that selection for different high immune responses had little effect on response to stress. Within line, however, significant negative correlations (-0.46
机译：在随机繁殖的对照系和先前从9个世代中选出的3种白色来亨鸡种系中测量3种不同的体内免疫反应的皮质酮血浆浓度：接种后3周对新城疫病毒疫苗的高抗体反应（ND3），高细胞介导的免疫反应（对植物血凝素，PHA的反应）和高吞噬活性（以碳清除率（CC）衡量）。该研究的目的是评估对免疫反应的选择是否对通过物理压力或注射促肾上腺皮质激素激素注射前后皮质酮浓度的评估来评估对应激反应的影响，以及该影响是否取决于已经存在的免疫反应性状。通过联合分析免疫应答和浓度来选择。品系间血浆皮质酮测量的平均值没有差异，表明选择不同的高免疫应答对应激反应的影响很小。然而，在4个品系中的3个品系中，在细胞介导的免疫力和皮质酮血浆浓度之间发现显着负相关（-0.46 <或= r <或= -0.39）。此外，在选择用于高抗体滴度（ND3-L）的品系中，皮质酮水平与ND3正相关（r = 0.41和0.47），而与CC负相关（r = -0.48）。

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